Browsing Clinical Studies by author "Zaidi, Shane Haider"

The Adequacy of Core Biopsy in the Assessment of Smooth Muscle Neoplasms of Soft Tissues: Implications for Treatment and Prognosis.

Schneider, N; Strauss, DC; Smith, MJ; Miah, AB; Zaidi, S; Benson, C; van Houdt, WJ; Jones, RL; Hayes, AJ; Fisher, C; Thway, K (2017-07)

The grading of soft tissue sarcomas is one of the most important prognostic factors and determines patient management. Although grading of most adult-type soft tissue sarcomas on biopsies correlates highly with the final ...

Clinical Characteristics and efficacy of chemotherapy in sclerosing epithelioid fibrosarcoma.

Chew, W; Benson, C; Thway, K; Hayes, A; Miah, A; Zaidi, S; Lee, ATJ; Messiou, C; Fisher, C; van der Graaf, WT; Jones, RL (2018-09-05)

BACKGROUND:Sclerosing epithelioid fibrosarcoma (SEF) is a very rare soft tissue sarcoma subtype. Clinically it is an aggressive tumour; however, to our knowledge there are no published reports regarding the efficacy of ...

Desmoid fibromatosis through the patients' eyes: time to change the focus and organisation of care?

Husson, O; Younger, E; Dunlop, A; Dean, L; Strauss, DC; Benson, C; Hayes, AJ; Miah, A; van Houdt, W; Zaidi, S; Smith, M; Williams, J; Jones, RL; van der Graaf, WTA (2019-03)

PURPOSE:Desmoid fibromatosis (DF) is a rare, unpredictable disease with no established, evidence-based treatments. Individual management is based on consensus algorithms. This study aimed to examine the specific health-related ...

Metastatic Soft Tissue Sarcomas in Adolescents and Young Adults: A Specialist Center Experience.

Younger, E; Husson, O; Asare, B; Benson, C; Judson, I; Miah, A; Zaidi, S; Dunlop, A; Al-Muderis, O; van Houdt, WJ; Jones, RL; van der Graaf, WTA (2020-05-05)

Purpose: Soft tissue sarcomas (STS) account for 8% of all cancers in adolescents and young adults (AYAs). Metastatic STS contribute significantly to disease-related mortality in this age group; however, data are limited ...

Pazopanib, a promising option for the treatment of aggressive fibromatosis.

Szucs, Z; Messiou, C; Wong, HH; Hatcher, H; Miah, A; Zaidi, S; van der Graaf, WTA; Judson, I; Jones, RL; Benson, C (2017-04)

Desmoid tumour/aggressive fibromatosis (DT/AF) is a rare soft-tissue neoplasm that is locally aggressive but does not metastasize. There is no standard systemic treatment for symptomatic patients, although a number of ...

Poor treatment outcomes with palliative gemcitabine and docetaxel chemotherapy in advanced and metastatic synovial sarcoma.

Pender, A; Davis, EJ; Chauhan, D; Messiou, C; Al-Muderis, O; Thway, K; Fisher, C; Zaidi, S; Miah, A; Judson, I; van der Graaf, W; Keedy, VL; Benson, C; Jones, RL (2018-08-20)

The outcome for patients with unresectable or metastatic soft tissue sarcoma remains poor with few treatment options. Synovial sarcoma is a rare type of sarcoma, predominantly affecting adolescents and young adults. Following ...

Rare Aggressive Behavior of MDM2-Amplified Retroperitoneal Dedifferentiated Liposarcoma, with Brain, Lung and Subcutaneous Metastases.

Ben Salha, I; Zaidi, S; Noujaim, J; Miah, AB; Fisher, C; Jones, RL; Thway, K (2016-09)

Dedifferentiated liposarcoma (DDL) is a histologically pleomorphic sarcoma, traditionally defined as well-differentiated liposarcoma with abrupt transition to high grade, non-lipogenic sarcoma. It can occur as part of ...

Recovery of Salivary Function: Contralateral Parotid-sparing Intensity-modulated Radiotherapy versus Bilateral Superficial Lobe Parotid-sparing Intensity-modulated Radiotherapy.

Miah, AB; Gulliford, SL; Morden, J; Newbold, KL; Bhide, SA; Zaidi, SH; Hall, E; Harrington, KJ; Nutting, CM (2016-09)

AIMS:To establish whether there is a difference in recovery of salivary function with bilateral superficial lobe parotid-sparing intensity-modulated radiotherapy (BSLPS-IMRT) versus contralateral parotid-sparing IMRT ...

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