Browsing Clinical Studies by author "Cheang, Chon"
Now showing items 41-44 of 44
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Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial.
Johnston, S; Puhalla, S; Wheatley, D; Ring, A; Barry, P; et al. (AMER SOC CLINICAL ONCOLOGY, 2019-01-20)PURPOSE: CDK4/6 inhibitors are used to treat estrogen receptor (ER)-positive metastatic breast cancer (BC) in combination with endocrine therapy. PALLET is a phase II randomized trial that evaluated the effects of combination ... -
Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.
Page, DB; Broeckx, G; Jahangir, CA; Verbandt, S; Gupta, RR; et al. (WILEY, 2023-08-01)Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized ... -
The use of digital pathology and image analysis in clinical trials.
Pell, R; Oien, K; Robinson, M; Pitman, H; Rajpoot, N; et al. (WILEY, 2019-04-01)Digital pathology and image analysis potentially provide greater accuracy, reproducibility and standardisation of pathology-based trial entry criteria and endpoints, alongside extracting new insights from both existing and ... -
αB-crystallin Expression in Breast Cancer is Associated with Brain Metastasis.
Voduc, KD; Nielsen, TO; Perou, CM; Harrell, JC; Fan, C; et al. (SPRINGERNATURE, 2015-10-21)BACKGROUND/OBJECTIVES: The molecular chaperone αB-crystallin is expressed in estrogen receptor, progesterone receptor and human epidermal growth factor receptor-2 "triple-negative" breast carcinomas and promotes brain and ...