The combination of vemurafenib and cobimetinib in advanced melanoma
MetadataShow full item record
Science & Technology
Life Sciences & Biomedicine
Pharmacology & Pharmacy
FREE SURVIVAL PFS
Melanoma and Kidney Cancer
License start date
EXPERT OPINION ON ORPHAN DRUGS, 2016, 4 (11), pp. 1105 - 1111 (7)
TAYLOR & FRANCIS LTD
Showing items related by title, author, creator and subject.
Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma. Pulido, J; Kottke, T; Thompson, J; Galivo, F; Wongthida, P; et al. (2012-03-18)Multiple intravenous injections of a cDNA library, derived from human melanoma cell lines and expressed using the highly immunogenic vector vesicular stomatitis virus (VSV), cured mice with established melanoma tumors. ...
Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy. Ilett, E; Kottke, T; Thompson, J; Rajani, K; Zaidi, S; et al. (2017-01)The anti-tumour effects associated with oncolytic virus therapy are mediated significantly through immune-mediated mechanisms, which depend both on the type of virus and the route of delivery. Here, we show that intra-tumoral ...