Browsing Molecular Pathology by author "Graham, Trevor"

Now showing items 21-22 of 22

    • The co-evolution of the genome and epigenome in colorectal cancer. 

      Heide, T; Househam, J; Cresswell, GD; Spiteri, I; Lynn, C; et al. (NATURE PORTFOLIO, 2022-11-24)
      Colorectal malignancies are a leading cause of cancer-related death1 and have undergone extensive genomic study2,3. However, DNA mutations alone do not fully explain malignant transformation4-7. Here we investigate the ...

    • Virtual alignment of pathology image series for multi-gigapixel whole slide images. 

      Gatenbee, CD; Baker, A-M; Prabhakaran, S; Swinyard, O; Slebos, RJC; et al. (NATURE PORTFOLIO, 2023-07-26)
      Interest in spatial omics is on the rise, but generation of highly multiplexed images remains challenging, due to cost, expertise, methodical constraints, and access to technology. An alternative approach is to register ...