Application of Liquid Biopsies in Cancer Targeted Therapy.
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Date
2017-11-01Author
Sumanasuriya, S
Lambros, MB
de Bono, JS
Type
Journal Article
Metadata
Show full item recordAbstract
As a growing body of evidence demonstrates intertumoral and intratumoral heterogeneity and clonal evolution, both during carcinogenesis and also throughout treatment resulting in acquired drug resistance, the utility of blood-based assays or "liquid biopsies" is becoming increasingly recognized in clinical practice and trial design. "Liquid biopsies" provide a less invasive approach to the current gold standard of interrogating tumors by tissue biopsies, which are frequently unfeasible, associated with morbidity, and cannot be performed as often.
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Subject
Animals
Humans
Neoplasms
DNA
Biopsy
Neoplastic Cells, Circulating
Research team
Cancer Biomarkers
Prostate Cancer Targeted Therapy Group
Language
eng
Date accepted
2017-06-01
License start date
2017-11
Citation
Clinical pharmacology and therapeutics, 2017, 102 (5), pp. 745 - 747
Publisher
WILEY