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An orally bioavailable Chk1 inhibitor, CCT244747, sensitizes bladder and head and neck cancer cell lines to radiation.
(2017-03)
Purpose Chk1 inhibition increases cell sensitivity to both chemotherapy and radiotherapy in several tumour types and is, therefore, a promising anti-cancer approach. Although several Chk1 inhibitors have been developed, ...
David Cosgrove OBITUARY
(2017-08-11)
Dosimetry-based treatment for Graves' disease.
(2018-06)
Objective The aim of this retrospective study was to assess the long-term outcome of a personalized dosimetry approach in Graves' disease aiming to render patients euthyroid from a planned thyroid absorbed dose of ...
Magnetic resonance imaging (MRI) guided radiotherapy for prostate cancer
(Institute of Cancer Research (University Of London), 2020-11-30)
Radiotherapy to the prostate involves increasingly sophisticated delivery techniques and changing fractionation schedules. Magnetic resonance imaging (MRI) guided radiotherapy allows daily adaptive replanning and can improve ...
Cross-modality deep learning: Contouring of MRI data from annotated CT data only.
(2020-11-30)
Purpose Online adaptive radiotherapy would greatly benefit from the development of reliable auto-segmentation algorithms for organs-at-risk and radiation targets. Current practice of manual segmentation is subjective and ...
Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part I: Intra-fraction breathing motion management.
(2020-12)
Purpose The POP-ART RT study aims to determine to what extent and how intra-fractional real-time respiratory motion management (RRMM) and plan adaptation for inter-fractional anatomical changes (ART), are used in clinical ...
UK Consensus on Normal Tissue Dose Constraints for Stereotactic Radiotherapy.
(2018-01)
Six UK studies investigating stereotactic ablative radiotherapy (SABR) are currently open. Many of these involve the treatment of oligometastatic disease at different locations in the body. Members of all the trial management ...
Statistical Motion Mask and Sliding Registration
(SPRINGER INTERNATIONAL PUBLISHING AG, 2018-01-01)
A Canadian approach to the regionalization of testis cancer: A review.
(2020-10)
At the Canadian Testis Cancer Workshop, the rationale and feasibility of regionalization of testis cancer care were discussed. The two-day workshop involved urologists, medical and radiation oncologists, pathologists, ...