New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer.
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Date
2018-01-01ICR Author
Author
Gouge, J
Vannini, A
Type
Journal Article
Metadata
Show full item recordAbstract
Here, we discuss the role of Brf2, an RNA Polymerase III core transcription factor, as a master switch of the oxidative stress response. We highlight the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations.
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Subject
Humans
Neoplasms
RNA Polymerase III
Transcription Factor TFIIIB
Transcription, Genetic
Oxidative Stress
Research team
Vannini Group
Language
eng
License start date
2018-01
Citation
Transcription, 2018, 9 (1), pp. 61 - 66
Publisher
TAYLOR & FRANCIS INC