New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer.
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Here, we discuss the role of Brf2, an RNA Polymerase III core transcription factor, as a master switch of the oxidative stress response. We highlight the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations.
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RNA polymerase III
RNA Polymerase III
Transcription Factor TFIIIB
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Transcription, 2018, 9 (1), pp. 61 - 66