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Systemic treatment in adult uterine sarcomas.

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Date
2018-02
ICR Author
van der Graaf, Wilhelmina
Author
Desar, IME
Ottevanger, PB
Benson, C
van der Graaf, WTA
Type
Journal Article
Metadata
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Abstract
Uterine sarcomas (US) are rare mesenchymal tumours of the uterus and are divided mainly into uterine leiomyosarcoma (uLMS), low grade endometrial stromal sarcoma (LG-ESS), high grade endometrial stromal sarcoma (HG-ESS), adenosarcomas and high grade undifferentiated sarcoma (HGUS). US are often high-grade tumours with a high local recurrence rate and metastatic risk. We here discuss the current standard of care and knowledge of systemic therapy for adult uterine sarcomas, in particular uLMS, LG-ESS, HG-ESS and HGUS, in both the adjuvant as well as the metastatic setting.
URI
https://repository.icr.ac.uk/handle/internal/977
DOI
https://doi.org/10.1016/j.critrevonc.2017.12.009
Collections
  • Clinical Studies
Subject
Humans
Sarcoma, Endometrial Stromal
Leiomyosarcoma
Sarcoma
Uterine Neoplasms
Endometrial Neoplasms
Chemotherapy, Adjuvant
Radiotherapy, Adjuvant
Adult
Female
Research team
Clinical and Translational Sarcoma
Language
eng
Date accepted
2017-12-12
License start date
2018-02
Citation
Critical reviews in oncology/hematology, 2018, 122 pp. 10 - 20

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