Now showing items 1-3 of 3

    • Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation. 

      Tape, CJ; Ling, S; Dimitriadi, M; McMahon, KM; Worboys, JD; et al. (CELL PRESS, 2016-06-16)
      Oncogenic mutations regulate signaling within both tumor cells and adjacent stromal cells. Here, we show that oncogenic KRAS (KRAS(G12D)) also regulates tumor cell signaling via stromal cells. By combining cell-specific ...
    • Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC. 

      Tape, CJ; Worboys, JD; Sinclair, J; Gourlay, R; Vogt, J; et al. (AMER CHEMICAL SOC, 2014-09-18)
      Reproducible, comprehensive phosphopeptide enrichment is essential for studying phosphorylation-regulated processes. Here, we describe the application of hyper-porous magnetic TiO2 and Ti-IMAC microspheres for uniform ...
    • Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome. 

      Worboys, JD; Sinclair, J; Yuan, Y; Jørgensen, C (NATURE PUBLISHING GROUP, 2014-10-01)
      In targeted proteomics it is critical that peptides are not only proteotypic but also accurately represent the level of the protein (quantotypic). Numerous approaches are used to identify proteotypic peptides, but quantotypic ...