Browsing ICR Divisions by author "Mandeville, Henry"
Now showing items 1-18 of 18
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Addition of dose-intensified doxorubicin to standard chemotherapy for rhabdomyosarcoma (EpSSG RMS 2005): a multicentre, open-label, randomised controlled, phase 3 trial.
Bisogno, G; Jenney, M; Bergeron, C; Gallego Melcón, S; Ferrari, A; et al. (ELSEVIER SCIENCE INC, 2018-08-01)BACKGROUND: Rhabdomyosarcoma is an aggressive tumour that can develop in almost any part of the body. Doxorubicin is an effective drug against rhabdomyosarcoma, but its role in combination with an established multidrug ... -
Alveolar rhabdomyosarcoma with regional nodal involvement: Results of a combined analysis from two cooperative groups.
Gallego, S; Chi, Y-Y; De Salvo, GL; Li, M; Merks, JHM; et al. (WILEY, 2021-03-01)BACKGROUND: Treatment of children and adolescents with alveolar rhabdomyosarcoma (ARMS) and regional nodal involvement (N1) have been approached differently by North American and European cooperative groups. In order to ... -
Brachytherapy for rhabdomyosarcoma: Survey of international clinical practice and development of guidelines.
Dávila Fajardo, R; Scarzello, G; Gaze, MN; Boterberg, T; Cameron, A; et al. (ELSEVIER IRELAND LTD, 2024-04-07)BACKGROUND AND PURPOSE: The purpose of this study was to address the lack of published data on the use of brachytherapy in pediatric rhabdomyosarcoma by describing current practice as starting point to develop consensus ... -
Clinical Implementation of Robust Multi-isocentric Volumetric Modulated Arc Radiotherapy for Craniospinal Irradiation.
Smyth, G; Mowat, S; Chia, K; Robinson, K; Warren-Oseni, K; et al. (ELSEVIER SCIENCE LONDON, 2022-04-01)AIMS: To determine if multi-isocentric volumetric modulated arc radiotherapy for craniospinal irradiation (CSI-VMAT) can be implemented safely and accurately using robust optimisation in a commercially available treatment ... -
Hypofractionated Stereotactic Ablative Radiotherapy for Recurrent or Oligometastatic Tumours in Children and Young Adults.
Chandy, E; Taylor, H; Gaito, S; Wells, E; Jones, C; et al.Aims Cancer remains a leading cause of death in children and adolescents in the developed world. Despite advances in oncological management, rates of primary treatment failure remain significant. Radiation of recurrent or ... -
In transit metastases in children, adolescents and young adults with localized rhabdomyosarcoma of the distal extremities: Analysis of the EpSSG RMS 2005 study.
Terwisscha van Scheltinga, CEJ; Wijnen, MHWA; Martelli, H; Guerin, F; Rogers, T; et al. (2022-03-12)In-transit metastases (ITM) are defined as metastatic lymph nodes or deposits occurring between the primary tumor and proximal draining lymph node basin. In extremity rhabdomyosarcoma (RMS), they have rarely been reported. ... -
Inter-clinician delineation variation for a new highly-conformal flank target volume in children with renal tumors: A SIOP-Renal Tumor Study Group international multicenter exercise.
Mul, J; Melchior, P; Seravalli, E; Saunders, D; Bolle, S; et al.Background and purpose Recently, the SIOP-RTSG developed a highly-conformal flank target volume definition for children with renal tumors. The aims of this study were to evaluate the inter-clinician delineation variation ... -
Local staging and treatment in extremity rhabdomyosarcoma. A report from the EpSSG-RMS2005 study.
Terwisscha van Scheltinga, SEJ; Wijnen, MHWA; Martelli, H; Rogers, T; Mandeville, H; et al.Rhabdomyosarcoma of the extremities present with two main challenges: correct evaluation of initial regional nodal involvement and define adequate local treatment. Methods Pediatric patients with localized rhabdomyosarcoma ... -
Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience.
Turcas, A; Kelly, SM; Bernier-Chastagner, V; Bolle, S; Cameron, A; et al. (Elsevier BV, 2023-10-01)Irradiation of the vertebrae in prepubertal patients, if non-homogenous, can result in future growth deformities including kyphoscoliosis. Vertebral delineation and dosimetry were assessed for 101 paediatric cases reviewed ... -
The need for consensus on delineation and dose constraints of dentofacial structures in paediatric radiotherapy: Outcomes of a SIOP Europe survey.
Davey, A; Pan, S; Bryce-Atkinson, A; Mandeville, H; Janssens, GO; et al. (ELSEVIER IRELAND LTD, 2023-11-01)BACKGROUND AND PURPOSE: Children receiving radiotherapy for head-and-neck tumours often experience severe dentofacial side effects. Despite this, recommendations for contouring and dose constraints to dentofacial structures ... -
Neurological Symptom Improvement After Re-Irradiation in Patients With Diffuse Intrinsic Pontine Glioma: A Retrospective Analysis of the SIOP-E-HGG/DIPG Project.
Chavaz, L; Janssens, GO; Bolle, S; Mandeville, H; Ramos-Albiac, M; et al. (FRONTIERS MEDIA SA, 2022-06-22)Purpose: The aim of this study is to investigate the spectrum of neurological triad improvement in patients with diffuse intrinsic pontine glioma (DIPG) treated by re-irradiation (re-RT) at first progression. Methods: We ... -
PAEDIATRIC RADIOTHERAPY IN ROMANIA- CURRENT PROVISION AND CHALLENGES: A SURVEY BY THE SIOP EUROPE QUARTET PROJECT
Turcas, A; Kelly, S; Blondeel, A; Chirila, M; Dana, C; et al. (WILEY, 2023-11-01) -
Quantitative diffusion-weighted MRI response assessment in rhabdomyosarcoma: an international retrospective study on behalf of the European paediatric Soft tissue sarcoma Study Group Imaging Committee.
van Ewijk, R; Chatziantoniou, C; Adams, M; Bertolini, P; Bisogno, G; et al. (SPRINGER, 2023-11-01)OBJECTIVE: To investigate the feasibility of diffusion-weighted magnetic resonance imaging (DW-MRI) as a predictive imaging marker after neoadjuvant chemotherapy in patients with rhabdomyosarcoma. MATERIAL AND METHODS: We ... -
QUARTET: A SIOP Europe project for quality and excellence in radiotherapy and imaging for children and adolescents with cancer.
Kelly, SM; Effeney, R; Gaze, MN; Bernier-Chastagner, V; Blondeel, A; et al. (ELSEVIER SCI LTD, 2022-09-01)The European Society for Paediatric Oncology (SIOPE) Radiation Oncology Working Group presents the QUARTET Project: a centralised quality assurance programme designed to standardise care and improve the quality of radiotherapy ... -
Radical radiotherapy for paediatric solid tumour metastases: An overview of current European protocols and outcomes of a SIOPE multicenter survey.
Huijskens, SC; Kroon, PS; Gaze, MN; Gandola, L; Bolle, S; et al.Purpose/objective About 20% of children with solid tumours (ST) present with distant metastases (DM). Evidence regarding the use of radical radiotherapy of these DM is sparse and open for personal interpretation. The aim ... -
A rapid review of evidence and recommendations from the SIOPE radiation oncology working group to help mitigate for reduced paediatric radiotherapy capacity during the COVID-19 pandemic or other crises.
Janssens, GO; Mandeville, HC; Timmermann, B; Maduro, JH; Alapetite, C; et al. (ELSEVIER IRELAND LTD, 2020-07-01)OBJECTIVE: To derive evidence-based recommendations for the optimal utilisation of resources during unexpected shortage of radiotherapy capacity. METHODS AND MATERIALS: We have undertaken a rapid review of published ... -
A step and shoot intensity modulated technique for total body irradiation.
Fog, LS; Hansen, VN; Kjær-Kristoffersen, F; Berlon, TE; Petersen, PM; et al. (Elsevier BV, 2019-06-01)INTRODUCTION: Total body irradiation (TBI) is a part of the conditioning regimen for bone marrow transplant.At the Royal Marsden (Sutton, UK) and Rigshospitalet (Copenhagen, Denmark), we introduced a step and shoot IMRT ... -
The potential role of MR-guided adaptive radiotherapy in pediatric oncology: Results from a SIOPE-COG survey.
Seravalli, E; Kroon, PS; Buatti, JM; Hall, MD; Mandeville, HC; et al.Background and purpose Magnetic resonance guided radiotherapy (MRgRT) has been successfully implemented for several routine clinical applications in adult patients. The purpose of this study is to map the potential benefit ...