Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience.
Date
2023-10-01ICR Author
Author
Turcas, A
Kelly, SM
Bernier-Chastagner, V
Bolle, S
Cameron, A
Corning, C
Clementel, E
Dieckmann, K
Davila Fajardo, R
Gaze, MN
Laprie, A
Magelssen, H
Meroni, S
Pignoli, E
Safwat, A
Scarzello, G
Talbot, J
Timmermann, B
Boterberg, T
Mandeville, HC
Type
Journal Article
Metadata
Show full item recordAbstract
Irradiation of the vertebrae in prepubertal patients, if non-homogenous, can result in future growth deformities including kyphoscoliosis. Vertebral delineation and dosimetry were assessed for 101 paediatric cases reviewed within QUARTET-affiliated trials. Despite the availability of published consensus guidelines, a high variability in vertebral delineation was observed, with impact on dosimetry.
Collections
Subject
Clinical trial
Pediatrics
Quality assurance
Radiotherapy
Vertebrae
Child
Humans
Forecasting
Radiation Oncology
Spine
Clinical Trials as Topic
Research team
Paed & Adolesc Radiother
Language
eng
Date accepted
2023-07-10
License start date
2023-10-01
Citation
Radiotherapy and Oncology, 2023, 187 pp. 109810 -
Publisher
Elsevier BV