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Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience.

dc.contributor.authorTurcas, A
dc.contributor.authorKelly, SM
dc.contributor.authorBernier-Chastagner, V
dc.contributor.authorBolle, S
dc.contributor.authorCameron, A
dc.contributor.authorCorning, C
dc.contributor.authorClementel, E
dc.contributor.authorDieckmann, K
dc.contributor.authorDavila Fajardo, R
dc.contributor.authorGaze, MN
dc.contributor.authorLaprie, A
dc.contributor.authorMagelssen, H
dc.contributor.authorMeroni, S
dc.contributor.authorPignoli, E
dc.contributor.authorSafwat, A
dc.contributor.authorScarzello, G
dc.contributor.authorTalbot, J
dc.contributor.authorTimmermann, B
dc.contributor.authorBoterberg, T
dc.contributor.authorMandeville, HC
dc.coverage.spatialIreland
dc.date.accessioned2023-10-02T11:37:56Z
dc.date.available2023-10-02T11:37:56Z
dc.date.issued2023-10-01
dc.identifier109810
dc.identifierS0167-8140(23)00367-5
dc.identifier.citationRadiotherapy and Oncology, 2023, 187 pp. 109810 -en_US
dc.identifier.issn0167-8140
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/6005
dc.identifier.eissn1879-0887
dc.identifier.eissn1879-0887
dc.identifier.doi10.1016/j.radonc.2023.109810
dc.description.abstractIrradiation of the vertebrae in prepubertal patients, if non-homogenous, can result in future growth deformities including kyphoscoliosis. Vertebral delineation and dosimetry were assessed for 101 paediatric cases reviewed within QUARTET-affiliated trials. Despite the availability of published consensus guidelines, a high variability in vertebral delineation was observed, with impact on dosimetry.
dc.formatPrint-Electronic
dc.format.extent109810 -
dc.languageeng
dc.language.isoengen_US
dc.publisherElsevier BVen_US
dc.relation.ispartofRadiotherapy and Oncology
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subjectClinical trial
dc.subjectPediatrics
dc.subjectQuality assurance
dc.subjectRadiotherapy
dc.subjectVertebrae
dc.subjectChild
dc.subjectHumans
dc.subjectForecasting
dc.subjectRadiation Oncology
dc.subjectSpine
dc.subjectClinical Trials as Topic
dc.titleManagement of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience.en_US
dc.typeJournal Article
dcterms.dateAccepted2023-07-10
dc.date.updated2023-10-02T11:37:17Z
rioxxterms.versionVoRen_US
rioxxterms.versionofrecord10.1016/j.radonc.2023.109810en_US
rioxxterms.licenseref.startdate2023-10-01
rioxxterms.typeJournal Article/Reviewen_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/37468069
pubs.organisational-groupICR
pubs.organisational-groupICR/Primary Group
pubs.organisational-groupICR/Primary Group/ICR Divisions
pubs.organisational-groupICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-groupICR/Primary Group/Royal Marsden Clinical Units
pubs.organisational-groupICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Paediatric and Adolescent Radiotherapy
pubs.publication-statusPublished
pubs.publisher-urlhttp://dx.doi.org/10.1016/j.radonc.2023.109810
pubs.volume187
icr.researchteamPaed & Adolesc Radiotheren_US
dc.contributor.icrauthorMandeville, Henry
icr.provenanceDeposited by Mr Arek Surman on 2023-10-02. Deposit type is initial. No. of files: 1. Files: 1-s2.0-S0167814023003675-main.pdf


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