Now showing items 1-20 of 51

    • Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers. 

      Schmidt, MK; Hogervorst, F; van Hien, R; Cornelissen, S; Broeks, A; Adank, MA; Meijers, H; Waisfisz, Q; Hollestelle, A; Schutte, M; van den Ouweland, A; Hooning, M; Andrulis, IL; Anton-Culver, H; Antonenkova, NN; Antoniou, AC; Arndt, V; Bermisheva, M; Bogdanova, NV; Bolla, MK; Brauch, H; Brenner, H; Brüning, T; Burwinkel, B; Chang-Claude, J; Chenevix-Trench, G; Couch, FJ; Cox, A; Cross, SS; Czene, K; Dunning, AM; Fasching, PA; Figueroa, J; Fletcher, O; Flyger, H; Galle, E; García-Closas, M; Giles, GG; Haeberle, L; Hall, P; Hillemanns, P; Hopper, JL; Jakubowska, A; John, EM; Jones, M; Khusnutdinova, E; Knight, JA; Kosma, V-M; Kristensen, V; Lee, A; Lindblom, A; Lubinski, J; Mannermaa, A; Margolin, S; Meindl, A; Milne, RL; Muranen, TA; Newcomb, PA; Offit, K; Park-Simon, T-W; Peto, J; Pharoah, PDP; Robson, M; Rudolph, A; Sawyer, EJ; Schmutzler, RK; Seynaeve, C; Soens, J; Southey, MC; Spurdle, AB; Surowy, H; Swerdlow, A; Tollenaar, RAEM; Tomlinson, I; Trentham-Dietz, A; Vachon, C; Wang, Q; Whittemore, AS; Ziogas, A; van der Kolk, L; Nevanlinna, H; Dörk, T; Bojesen, S; Easton, DF (2016-08)
      PURPOSE:CHEK2*1100delC is a well-established breast cancer risk variant that is most prevalent in European populations; however, there are limited data on risk of breast cancer by age and tumor subtype, which limits its ...
    • Analgesic Use and Ovarian Cancer Risk: An Analysis in the Ovarian Cancer Cohort Consortium. 

      Trabert, B; Poole, EM; White, E; Visvanathan, K; Adami, H-O; Anderson, GL; Brasky, TM; Brinton, LA; Fortner, RT; Gaudet, M; Hartge, P; Hoffman-Bolton, J; Jones, M; Lacey, JV; Larsson, SC; Mackenzie, GG; Schouten, LJ; Sandler, DP; O'Brien, K; Patel, AV; Peters, U; Prizment, A; Robien, K; Setiawan, VW; Swerdlow, A; van den Brandt, PA; Weiderpass, E; Wilkens, LR; Wolk, A; Wentzensen, N; Tworoger, SS; Ovarian Cancer Cohort Consortium (OC3) (2019-02)
      BACKGROUND:Aspirin use is associated with reduced risk of several cancers. A pooled analysis of 12 case-control studies showed a 10% decrease in ovarian cancer risk with regular aspirin use, which was stronger for daily ...
    • Association analysis identifies 65 new breast cancer risk loci. 

      Michailidou, K; Lindström, S; Dennis, J; Beesley, J; Hui, S; Kar, S; Lemaçon, A; Soucy, P; Glubb, D; Rostamianfar, A; Bolla, MK; Wang, Q; Tyrer, J; Dicks, E; Lee, A; Wang, Z; Allen, J; Keeman, R; Eilber, U; French, JD; Qing Chen, X; Fachal, L; McCue, K; McCart Reed, AE; Ghoussaini, M; Carroll, JS; Jiang, X; Finucane, H; Adams, M; Adank, MA; Ahsan, H; Aittomäki, K; Anton-Culver, H; Antonenkova, NN; Arndt, V; Aronson, KJ; Arun, B; Auer, PL; Bacot, F; Barrdahl, M; Baynes, C; Beckmann, MW; Behrens, S; Benitez, J; Bermisheva, M; Bernstein, L; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bonanni, B; Børresen-Dale, A-L; Brand, JS; Brauch, H; Brennan, P; Brenner, H; Brinton, L; Broberg, P; Brock, IW; Broeks, A; Brooks-Wilson, A; Brucker, SY; Brüning, T; Burwinkel, B; Butterbach, K; Cai, Q; Cai, H; Caldés, T; Canzian, F; Carracedo, A; Carter, BD; Castelao, JE; Chan, TL; David Cheng, T-Y; Seng Chia, K; Choi, J-Y; Christiansen, H; Clarke, CL; NBCS Collaborators; Collée, M; Conroy, DM; Cordina-Duverger, E; Cornelissen, S; Cox, DG; Cox, A; Cross, SS; Cunningham, JM; Czene, K; Daly, MB; Devilee, P; Doheny, KF; Dörk, T; Dos-Santos-Silva, I; Dumont, M; Durcan, L; Dwek, M; Eccles, DM; Ekici, AB; Eliassen, AH; Ellberg, C; Elvira, M; Engel, C; Eriksson, M; Fasching, PA; Figueroa, J; Flesch-Janys, D; Fletcher, O; Flyger, H; Fritschi, L; Gaborieau, V; Gabrielson, M; Gago-Dominguez, M; Gao, Y-T; Gapstur, SM; García-Sáenz, JA; Gaudet, MM; Georgoulias, V; Giles, GG; Glendon, G; Goldberg, MS; Goldgar, DE; González-Neira, A; Grenaker Alnæs, GI; Grip, M; Gronwald, J; Grundy, A; Guénel, P; Haeberle, L; Hahnen, E; Haiman, CA; Håkansson, N; Hamann, U; Hamel, N; Hankinson, S; Harrington, P; Hart, SN; Hartikainen, JM; Hartman, M; Hein, A; Heyworth, J; Hicks, B; Hillemanns, P; Ho, DN; Hollestelle, A; Hooning, MJ; Hoover, RN; Hopper, JL; Hou, M-F; Hsiung, C-N; Huang, G; Humphreys, K; Ishiguro, J; Ito, H; Iwasaki, M; Iwata, H; Jakubowska, A; Janni, W; John, EM; Johnson, N; Jones, K; Jones, M; Jukkola-Vuorinen, A; Kaaks, R; Kabisch, M; Kaczmarek, K; Kang, D; Kasuga, Y; Kerin, MJ; Khan, S; Khusnutdinova, E; Kiiski, JI; Kim, S-W; Knight, JA; Kosma, V-M; Kristensen, VN; Krüger, U; Kwong, A; Lambrechts, D; Le Marchand, L; Lee, E; Lee, MH; Lee, JW; Neng Lee, C; Lejbkowicz, F; Li, J; Lilyquist, J; Lindblom, A; Lissowska, J; Lo, W-Y; Loibl, S; Long, J; Lophatananon, A; Lubinski, J; Luccarini, C; Lux, MP; Ma, ESK; MacInnis, RJ; Maishman, T; Makalic, E; Malone, KE; Kostovska, IM; Mannermaa, A; Manoukian, S; Manson, JE; Margolin, S; Mariapun, S; Martinez, ME; Matsuo, K; Mavroudis, D; McKay, J; McLean, C; Meijers-Heijboer, H; Meindl, A; Menéndez, P; Menon, U; Meyer, J; Miao, H; Miller, N; Taib, NAM; Muir, K; Mulligan, AM; Mulot, C; Neuhausen, SL; Nevanlinna, H; Neven, P; Nielsen, SF; Noh, D-Y; Nordestgaard, BG; Norman, A; Olopade, OI; Olson, JE; Olsson, H; Olswold, C; Orr, N; Pankratz, VS; Park, SK; Park-Simon, T-W; Lloyd, R; Perez, JIA; Peterlongo, P; Peto, J; Phillips, K-A; Pinchev, M; Plaseska-Karanfilska, D; Prentice, R; Presneau, N; Prokofyeva, D; Pugh, E; Pylkäs, K; Rack, B; Radice, P; Rahman, N; Rennert, G; Rennert, HS; Rhenius, V; Romero, A; Romm, J; Ruddy, KJ; Rüdiger, T; Rudolph, A; Ruebner, M; Rutgers, EJT; Saloustros, E; Sandler, DP; Sangrajrang, S; Sawyer, EJ; Schmidt, DF; Schmutzler, RK; Schneeweiss, A; Schoemaker, MJ; Schumacher, F; Schürmann, P; Scott, RJ; Scott, C; Seal, S; Seynaeve, C; Shah, M; Sharma, P; Shen, C-Y; Sheng, G; Sherman, ME; Shrubsole, MJ; Shu, X-O; Smeets, A; Sohn, C; Southey, MC; Spinelli, JJ; Stegmaier, C; Stewart-Brown, S; Stone, J; Stram, DO; Surowy, H; Swerdlow, A; Tamimi, R; Taylor, JA; Tengström, M; Teo, SH; Beth Terry, M; Tessier, DC; Thanasitthichai, S; Thöne, K; Tollenaar, RAEM; Tomlinson, I; Tong, L; Torres, D; Truong, T; Tseng, C-C; Tsugane, S; Ulmer, H-U; Ursin, G; Untch, M; Vachon, C; van Asperen, CJ; Van Den Berg, D; van den Ouweland, AMW; van der Kolk, L; van der Luijt, RB; Vincent, D; Vollenweider, J; Waisfisz, Q; Wang-Gohrke, S; Weinberg, CR; Wendt, C; Whittemore, AS; Wildiers, H; Willett, W; Winqvist, R; Wolk, A; Wu, AH; Xia, L; Yamaji, T; Yang, XR; Har Yip, C; Yoo, K-Y; Yu, J-C; Zheng, W; Zheng, Y; Zhu, B; Ziogas, A; Ziv, E; ABCTB Investigators; ConFab/AOCS Investigators; Lakhani, SR; Antoniou, AC; Droit, A; Andrulis, IL; Amos, CI; Couch, FJ; Pharoah, PDP; Chang-Claude, J; Hall, P; Hunter, DJ; Milne, RL; García-Closas, M; Schmidt, MK; Chanock, SJ; Dunning, AM; Edwards, SL; Bader, GD; Chenevix-Trench, G; Simard, J; Kraft, P; Easton, DF (2017-11)
      Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer risk remains unknown. ...
    • Association of Body Mass Index and Age With Subsequent Breast Cancer Risk in Premenopausal Women. 

      Premenopausal Breast Cancer Collaborative Group; Schoemaker, MJ; Nichols, HB; Wright, LB; Brook, MN; Jones, ME; O'Brien, KM; Adami, H-O; Baglietto, L; Bernstein, L; Bertrand, KA; Boutron-Ruault, M-C; Braaten, T; Chen, Y; Connor, AE; Dorronsoro, M; Dossus, L; Eliassen, AH; Giles, GG; Hankinson, SE; Kaaks, R; Key, TJ; Kirsh, VA; Kitahara, CM; Koh, W-P; Larsson, SC; Linet, MS; Ma, H; Masala, G; Merritt, MA; Milne, RL; Overvad, K; Ozasa, K; Palmer, JR; Peeters, PH; Riboli, E; Rohan, TE; Sadakane, A; Sund, M; Tamimi, RM; Trichopoulou, A; Ursin, G; Vatten, L; Visvanathan, K; Weiderpass, E; Willett, WC; Wolk, A; Yuan, J-M; Zeleniuch-Jacquotte, A; Sandler, DP; Swerdlow, AJ (2018-11-01)
      Importance: The association between increasing body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) and risk of breast cancer is unique in cancer epidemiology in that a crossover ...
    • Association of Body Mass Index and Age With Subsequent Breast Cancer Risk in Premenopausal Women. 

      Premenopausal Breast Cancer Collaborative Group; Schoemaker, MJ; Nichols, HB; Wright, LB; Brook, MN; Jones, ME; O'Brien, KM; Adami, H-O; Baglietto, L; Bernstein, L; Bertrand, KA; Boutron-Ruault, M-C; Braaten, T; Chen, Y; Connor, AE; Dorronsoro, M; Dossus, L; Eliassen, AH; Giles, GG; Hankinson, SE; Kaaks, R; Key, TJ; Kirsh, VA; Kitahara, CM; Koh, W-P; Larsson, SC; Linet, MS; Ma, H; Masala, G; Merritt, MA; Milne, RL; Overvad, K; Ozasa, K; Palmer, JR; Peeters, PH; Riboli, E; Rohan, TE; Sadakane, A; Sund, M; Tamimi, RM; Trichopoulou, A; Ursin, G; Vatten, L; Visvanathan, K; Weiderpass, E; Willett, WC; Wolk, A; Yuan, J-M; Zeleniuch-Jacquotte, A; Sandler, DP; Swerdlow, AJ (2018-11-08)
      Importance:The association between increasing body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) and risk of breast cancer is unique in cancer epidemiology in that a crossover ...
    • Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21. 

      Hamdi, Y; Soucy, P; Adoue, V; Michailidou, K; Canisius, S; Lemaçon, A; Droit, A; Andrulis, IL; Anton-Culver, H; Arndt, V; Baynes, C; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bolla, MK; Bonanni, B; Borresen-Dale, A-L; Brand, JS; Brauch, H; Brenner, H; Broeks, A; Burwinkel, B; Chang-Claude, J; NBCS Collaborators; Couch, FJ; Cox, A; Cross, SS; Czene, K; Darabi, H; Dennis, J; Devilee, P; Dörk, T; Dos-Santos-Silva, I; Eriksson, M; Fasching, PA; Figueroa, J; Flyger, H; García-Closas, M; Giles, GG; Goldberg, MS; González-Neira, A; Grenaker-Alnæs, G; Guénel, P; Haeberle, L; Haiman, CA; Hamann, U; Hallberg, E; Hooning, MJ; Hopper, JL; Jakubowska, A; Jones, M; Kabisch, M; Kataja, V; Lambrechts, D; Le Marchand, L; Lindblom, A; Lubinski, J; Mannermaa, A; Maranian, M; Margolin, S; Marme, F; Milne, RL; Neuhausen, SL; Nevanlinna, H; Neven, P; Olswold, C; Peto, J; Plaseska-Karanfilska, D; Pylkäs, K; Radice, P; Rudolph, A; Sawyer, EJ; Schmidt, MK; Shu, X-O; Southey, MC; Swerdlow, A; Tollenaar, RAEM; Tomlinson, I; Torres, D; Truong, T; Vachon, C; Van Den Ouweland, AMW; Wang, Q; Winqvist, R; kConFab/AOCS Investigators; Zheng, W; Benitez, J; Chenevix-Trench, G; Dunning, AM; Pharoah, PDP; Kristensen, V; Hall, P; Easton, DF; Pastinen, T; Nord, S; Simard, J (2016-12)
      There are significant inter-individual differences in the levels of gene expression. Through modulation of gene expression, cis-acting variants represent an important source of phenotypic variation. Consequently, cis-regulatory ...
    • Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study. 

      Rambau, PF; Vierkant, RA; Intermaggio, MP; Kelemen, LE; Goodman, MT; Herpel, E; Pharoah, PD; Kommoss, S; Jimenez-Linan, M; Karlan, BY; Gentry-Maharaj, A; Menon, U; Polo, SH; Candido Dos Reis, FJ; Doherty, JA; Gayther, SA; Sharma, R; Larson, MC; Harnett, PR; Hatfield, E; de Andrade, JM; Nelson, GS; Steed, H; Schildkraut, JM; Carney, ME; Høgdall, E; Whittemore, AS; Widschwendter, M; Kennedy, CJ; Wang, F; Wang, Q; Wang, C; Armasu, SM; Daley, F; Coulson, P; Jones, ME; Anglesio, MS; Chow, C; de Fazio, A; García-Closas, M; Brucker, SY; Cybulski, C; Harris, HR; Hartkopf, AD; Huzarski, T; Jensen, A; Lubiński, J; Oszurek, O; Benitez, J; Mina, F; Staebler, A; Taran, FA; Pasternak, J; Talhouk, A; Rossing, MA; Hendley, J; AOCS Group; Edwards, RP; Fereday, S; Modugno, F; Ness, RB; Sieh, W; El-Bahrawy, MA; Winham, SJ; Lester, J; Kjaer, SK; Gronwald, J; Sinn, P; Fasching, PA; Chang-Claude, J; Moysich, KB; Bowtell, DD; Hernandez, BY; Luk, H; Behrens, S; Shah, M; Jung, A; Ghatage, P; Alsop, J; Alsop, K; García-Donas, J; Thompson, PJ; Swerdlow, AJ; Karpinskyj, C; Cazorla-Jiménez, A; García, MJ; Deen, S; Wilkens, LR; Palacios, J; Berchuck, A; Koziak, JM; Brenton, JD; Cook, LS; Goode, EL; Huntsman, DG; Ramus, SJ; Köbel, M (2018-10)
      We aimed to validate the prognostic association of p16 expression in ovarian high-grade serous carcinomas (HGSC) and to explore it in other ovarian carcinoma histotypes. p16 protein expression was assessed by clinical-grade ...
    • Breast Cancer Risk After Recent Childbirth: A Pooled Analysis of 15 Prospective Studies. 

      Nichols, HB; Schoemaker, MJ; Cai, J; Xu, J; Wright, LB; Brook, MN; Jones, ME; Adami, H-O; Baglietto, L; Bertrand, KA; Blot, WJ; Boutron-Ruault, M-C; Dorronsoro, M; Dossus, L; Eliassen, AH; Giles, GG; Gram, IT; Hankinson, SE; Hoffman-Bolton, J; Kaaks, R; Key, TJ; Kitahara, CM; Larsson, SC; Linet, M; Merritt, MA; Milne, RL; Pala, V; Palmer, JR; Peeters, PH; Riboli, E; Sund, M; Tamimi, RM; Tjønneland, A; Trichopoulou, A; Ursin, G; Vatten, L; Visvanathan, K; Weiderpass, E; Wolk, A; Zheng, W; Weinberg, CR; Swerdlow, AJ; Sandler, DP (2019-01)
      Background:Parity is widely recognized as protective for breast cancer, but breast cancer risk may be increased shortly after childbirth. Whether this risk varies with breastfeeding, family history of breast cancer, or ...
    • Breast cancer risk following Hodgkin lymphoma radiotherapy in relation to menstrual and reproductive factors. 

      Cooke, R; Jones, ME; Cunningham, D; Falk, SJ; Gilson, D; Hancock, BW; Harris, SJ; Horwich, A; Hoskin, PJ; Illidge, T; Linch, DC; Lister, TA; Lucraft, HH; Radford, JA; Stevens, AM; Syndikus, I; Williams, MV; England and Wales Hodgkin Lymphoma Follow-up Group; Swerdlow, AJ (2013-06)
      BACKGROUND: Women treated with supradiaphragmatic radiotherapy (sRT) for Hodgkin lymphoma (HL) at young ages have a substantially increased breast cancer risk. Little is known about how menarcheal and reproductive factors ...
    • Breast cancer risk in relation to history of preeclampsia and hyperemesis gravidarum: Prospective analysis in the Generations Study. 

      Wright, LB; Schoemaker, MJ; Jones, ME; Ashworth, A; Swerdlow, AJ (2018-08)
      Preeclampsia and hyperemesis gravidarum are pregnancy complications associated with altered sex hormone levels. Previous studies suggest preeclampsia may be associated with a decreased risk of subsequent breast cancer and ...
    • Childhood body size and pubertal timing in relation to adult mammographic density phenotype. 

      Schoemaker, MJ; Jones, ME; Allen, S; Hoare, J; Ashworth, A; Dowsett, M; Swerdlow, AJ (2017-02-07)
      BACKGROUND:An earlier age at onset of breast development and longer time between pubertal stages has been implicated in breast cancer risk. It is not clear whether associations of breast cancer risk with puberty or predictors ...
    • Circulating Vitamin D and Colorectal Cancer Risk: An International Pooling Project of 17 Cohorts. 

      McCullough, ML; Zoltick, ES; Weinstein, SJ; Fedirko, V; Wang, M; Cook, NR; Eliassen, AH; Zeleniuch-Jacquotte, A; Agnoli, C; Albanes, D; Barnett, MJ; Buring, JE; Campbell, PT; Clendenen, TV; Freedman, ND; Gapstur, SM; Giovannucci, EL; Goodman, GG; Haiman, CA; Ho, GYF; Horst, RL; Hou, T; Huang, W-Y; Jenab, M; Jones, ME; Joshu, CE; Krogh, V; Lee, I-M; Lee, JE; Männistö, S; Le Marchand, L; Mondul, AM; Neuhouser, ML; Platz, EA; Purdue, MP; Riboli, E; Robsahm, TE; Rohan, TE; Sasazuki, S; Schoemaker, MJ; Sieri, S; Stampfer, MJ; Swerdlow, AJ; Thomson, CA; Tretli, S; Tsugane, S; Ursin, G; Visvanathan, K; White, KK; Wu, K; Yaun, S-S; Zhang, X; Willett, WC; Gail, MH; Ziegler, RG; Smith-Warner, SA (2019-02)
      BACKGROUND:Experimental and epidemiological studies suggest a protective role for vitamin D in colorectal carcinogenesis, but evidence is inconclusive. Circulating 25-hydroxyvitamin D (25(OH)D) concentrations that minimize ...
    • Comparative Validation of Breast Cancer Risk Prediction Models and Projections for Future Risk Stratification. 

      Pal Choudhury, P; Wilcox, AN; Brook, MN; Zhang, Y; Ahearn, T; Orr, N; Coulson, P; Schoemaker, MJ; Jones, ME; Gail, MH; Swerdlow, AJ; Chatterjee, N; Garcia-Closas, M (2020-03)
      BACKGROUND:External validation of risk models is critical for risk-stratified breast cancer prevention. We used the Individualized Coherent Absolute Risk Estimation (iCARE) as a flexible tool for risk model development and ...
    • Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study. 

      Johns, LE; Jones, ME; Schoemaker, MJ; McFadden, E; Ashworth, A; Swerdlow, AJ (2018-02)
      BACKGROUND:Circadian disruption caused by exposure to light at night (LAN) has been proposed as a risk factor for breast cancer and a reason for secular increases in incidence. Studies to date have largely been ecological ...
    • E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium. 

      Horne, HN; Oh, H; Sherman, ME; Palakal, M; Hewitt, SM; Schmidt, MK; Milne, RL; Hardisson, D; Benitez, J; Blomqvist, C; Bolla, MK; Brenner, H; Chang-Claude, J; Cora, R; Couch, FJ; Cuk, K; Devilee, P; Easton, DF; Eccles, DM; Eilber, U; Hartikainen, JM; Heikkilä, P; Holleczek, B; Hooning, MJ; Jones, M; Keeman, R; Mannermaa, A; Martens, JWM; Muranen, TA; Nevanlinna, H; Olson, JE; Orr, N; Perez, JIA; Pharoah, PDP; Ruddy, KJ; Saum, K-U; Schoemaker, MJ; Seynaeve, C; Sironen, R; Smit, VTHBM; Swerdlow, AJ; Tengström, M; Thomas, AS; Timmermans, AM; Tollenaar, RAEM; Troester, MA; van Asperen, CJ; van Deurzen, CHM; Van Leeuwen, FF; Van't Veer, LJ; García-Closas, M; Figueroa, JD (2018-04-26)
      E-cadherin (CDH1) is a putative tumor suppressor gene implicated in breast carcinogenesis. Yet, whether risk factors or survival differ by E-cadherin tumor expression is unclear. We evaluated E-cadherin tumor immunohistochemistry ...
    • Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk. 

      Johansson, A; Palli, D; Masala, G; Grioni, S; Agnoli, C; Tumino, R; Giurdanella, MC; Fasanelli, F; Sacerdote, C; Panico, S; Mattiello, A; Polidoro, S; Jones, ME; Schoemaker, MJ; Orr, N; Tomczyk, K; Johnson, N; Fletcher, O; Perduca, V; Baglietto, L; Dugué, P-A; Southey, MC; Giles, GG; English, DR; Milne, RL; Severi, G; Ambatipudi, S; Cuenin, C; Chajès, V; Romieu, I; Herceg, Z; Swerdlow, AJ; Vineis, P; Flanagan, JM (2019-04-30)
      BACKGROUND:It is well established that estrogens and other hormonal factors influence breast cancer susceptibility. We hypothesized that a woman's total lifetime estrogen exposure accumulates changes in DNA methylation, ...
    • Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation. 

      Abubakar, M; Chang-Claude, J; Ali, HR; Chatterjee, N; Coulson, P; Daley, F; Blows, F; Benitez, J; Milne, RL; Brenner, H; Stegmaier, C; Mannermaa, A; Rudolph, A; Sinn, P; Couch, FJ; Devilee, P; Tollenaar, RAEM; Seynaeve, C; Figueroa, J; Lissowska, J; Hewitt, S; Hooning, MJ; Hollestelle, A; Foekens, R; Koppert, LB; kConFab Investigators; Bolla, MK; Wang, Q; Jones, ME; Schoemaker, MJ; Keeman, R; Easton, DF; Swerdlow, AJ; Sherman, ME; Schmidt, MK; Pharoah, PD; Garcia-Closas, M (2018-08)
      Limited epidemiological evidence suggests that the etiology of hormone receptor positive (HR+) breast cancer may differ by levels of histologic grade and proliferation. We pooled risk factor and pathology data on 5,905 HR+ ...
    • Family history and risk of breast cancer: an analysis accounting for family structure. 

      Brewer, HR; Jones, ME; Schoemaker, MJ; Ashworth, A; Swerdlow, AJ (2017-08)
      Family history is an important risk factor for breast cancer incidence, but the parameters conventionally used to categorize it are based solely on numbers and/or ages of breast cancer cases in the family and take no account ...
    • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. 

      Fachal, L; Aschard, H; Beesley, J; Barnes, DR; Allen, J; Kar, S; Pooley, KA; Dennis, J; Michailidou, K; Turman, C; Soucy, P; Lemaçon, A; Lush, M; Tyrer, JP; Ghoussaini, M; Moradi Marjaneh, M; Jiang, X; Agata, S; Aittomäki, K; Alonso, MR; Andrulis, IL; Anton-Culver, H; Antonenkova, NN; Arason, A; Arndt, V; Aronson, KJ; Arun, BK; Auber, B; Auer, PL; Azzollini, J; Balmaña, J; Barkardottir, RB; Barrowdale, D; Beeghly-Fadiel, A; Benitez, J; Bermisheva, M; Białkowska, K; Blanco, AM; Blomqvist, C; Blot, W; Bogdanova, NV; Bojesen, SE; Bolla, MK; Bonanni, B; Borg, A; Bosse, K; Brauch, H; Brenner, H; Briceno, I; Brock, IW; Brooks-Wilson, A; Brüning, T; Burwinkel, B; Buys, SS; Cai, Q; Caldés, T; Caligo, MA; Camp, NJ; Campbell, I; Canzian, F; Carroll, JS; Carter, BD; Castelao, JE; Chiquette, J; Christiansen, H; Chung, WK; Claes, KBM; Clarke, CL; GEMO Study Collaborators; EMBRACE Collaborators; Collée, JM; Cornelissen, S; Couch, FJ; Cox, A; Cross, SS; Cybulski, C; Czene, K; Daly, MB; de la Hoya, M; Devilee, P; Diez, O; Ding, YC; Dite, GS; Domchek, SM; Dörk, T; Dos-Santos-Silva, I; Droit, A; Dubois, S; Dumont, M; Duran, M; Durcan, L; Dwek, M; Eccles, DM; Engel, C; Eriksson, M; Evans, DG; Fasching, PA; Fletcher, O; Floris, G; Flyger, H; Foretova, L; Foulkes, WD; Friedman, E; Fritschi, L; Frost, D; Gabrielson, M; Gago-Dominguez, M; Gambino, G; Ganz, PA; Gapstur, SM; Garber, J; García-Sáenz, JA; Gaudet, MM; Georgoulias, V; Giles, GG; Glendon, G; Godwin, AK; Goldberg, MS; Goldgar, DE; González-Neira, A; Tibiletti, MG; Greene, MH; Grip, M; Gronwald, J; Grundy, A; Guénel, P; Hahnen, E; Haiman, CA; Håkansson, N; Hall, P; Hamann, U; Harrington, PA; Hartikainen, JM; Hartman, M; He, W; Healey, CS; Heemskerk-Gerritsen, BAM; Heyworth, J; Hillemanns, P; Hogervorst, FBL; Hollestelle, A; Hooning, MJ; Hopper, JL; Howell, A; Huang, G; Hulick, PJ; Imyanitov, EN; KConFab Investigators; HEBON Investigators; ABCTB Investigators; Isaacs, C; Iwasaki, M; Jager, A; Jakimovska, M; Jakubowska, A; James, PA; Janavicius, R; Jankowitz, RC; John, EM; Johnson, N; Jones, ME; Jukkola-Vuorinen, A; Jung, A; Kaaks, R; Kang, D; Kapoor, PM; Karlan, BY; Keeman, R; Kerin, MJ; Khusnutdinova, E; Kiiski, JI; Kirk, J; Kitahara, CM; Ko, Y-D; Konstantopoulou, I; Kosma, V-M; Koutros, S; Kubelka-Sabit, K; Kwong, A; Kyriacou, K; Laitman, Y; Lambrechts, D; Lee, E; Leslie, G; Lester, J; Lesueur, F; Lindblom, A; Lo, W-Y; Long, J; Lophatananon, A; Loud, JT; Lubiński, J; MacInnis, RJ; Maishman, T; Makalic, E; Mannermaa, A; Manoochehri, M; Manoukian, S; Margolin, S; Martinez, ME; Matsuo, K; Maurer, T; Mavroudis, D; Mayes, R; McGuffog, L; McLean, C; Mebirouk, N; Meindl, A; Miller, A; Miller, N; Montagna, M; Moreno, F; Muir, K; Mulligan, AM; Muñoz-Garzon, VM; Muranen, TA; Narod, SA; Nassir, R; Nathanson, KL; Neuhausen, SL; Nevanlinna, H; Neven, P; Nielsen, FC; Nikitina-Zake, L; Norman, A; Offit, K; Olah, E; Olopade, OI; Olsson, H; Orr, N; Osorio, A; Pankratz, VS; Papp, J; Park, SK; Park-Simon, T-W; Parsons, MT; Paul, J; Pedersen, IS; Peissel, B; Peshkin, B; Peterlongo, P; Peto, J; Plaseska-Karanfilska, D; Prajzendanc, K; Prentice, R; Presneau, N; Prokofyeva, D; Pujana, MA; Pylkäs, K; Radice, P; Ramus, SJ; Rantala, J; Rau-Murthy, R; Rennert, G; Risch, HA; Robson, M; Romero, A; Rossing, M; Saloustros, E; Sánchez-Herrero, E; Sandler, DP; Santamariña, M; Saunders, C; Sawyer, EJ; Scheuner, MT; Schmidt, DF; Schmutzler, RK; Schneeweiss, A; Schoemaker, MJ; Schöttker, B; Schürmann, P; Scott, C; Scott, RJ; Senter, L; Seynaeve, CM; Shah, M; Sharma, P; Shen, C-Y; Shu, X-O; Singer, CF; Slavin, TP; Smichkoska, S; Southey, MC; Spinelli, JJ; Spurdle, AB; Stone, J; Stoppa-Lyonnet, D; Sutter, C; Swerdlow, AJ; Tamimi, RM; Tan, YY; Tapper, WJ; Taylor, JA; Teixeira, MR; Tengström, M; Teo, SH; Terry, MB; Teulé, A; Thomassen, M; Thull, DL; Tischkowitz, M; Toland, AE; Tollenaar, RAEM; Tomlinson, I; Torres, D; Torres-Mejía, G; Troester, MA; Truong, T; Tung, N; Tzardi, M; Ulmer, H-U; Vachon, CM; van Asperen, CJ; van der Kolk, LE; van Rensburg, EJ; Vega, A; Viel, A; Vijai, J; Vogel, MJ; Wang, Q; Wappenschmidt, B; Weinberg, CR; Weitzel, JN; Wendt, C; Wildiers, H; Winqvist, R; Wolk, A; Wu, AH; Yannoukakos, D; Zhang, Y; Zheng, W; Hunter, D; Pharoah, PDP; Chang-Claude, J; García-Closas, M; Schmidt, MK; Milne, RL; Kristensen, VN; French, JD; Edwards, SL; Antoniou, AC; Chenevix-Trench, G; Simard, J; Easton, DF; Kraft, P; Dunning, AM (2020-01-07)
      Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association ...
    • Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study. 

      Johnson, N; Dudbridge, F; Orr, N; Gibson, L; Jones, ME; Schoemaker, MJ; Folkerd, EJ; Haynes, BP; Hopper, JL; Southey, MC; Dite, GS; Apicella, C; Schmidt, MK; Broeks, A; Van't Veer, LJ; Atsma, F; Muir, K; Lophatananon, A; Fasching, PA; Beckmann, MW; Ekici, AB; Renner, SP; Sawyer, E; Tomlinson, I; Kerin, M; Miller, N; Burwinkel, B; Marme, F; Schneeweiss, A; Sohn, C; Guénel, P; Truong, T; Cordina, E; Menegaux, F; Bojesen, SE; Nordestgaard, BG; Flyger, H; Milne, R; Zamora, MP; Arias Perez, JI; Benitez, J; Bernstein, L; Anton-Culver, H; Ziogas, A; Clarke Dur, C; Brenner, H; Müller, H; Arndt, V; Dieffenbach, AK; Meindl, A; Heil, J; Bartram, CR; Schmutzler, RK; Brauch, H; Justenhoven, C; Ko, Y-D; GENICA (Gene Environment Interaction and Breast Cancer in Germany) Network; Nevanlinna, H; Muranen, TA; Aittomäki, K; Blomqvist, C; Matsuo, K; Dörk, T; Bogdanova, NV; Antonenkova, NN; Lindblom, A; Mannermaa, A; Kataja, V; Kosma, V-M; Hartikainen, JM; Chenevix-Trench, G; Beesley, J; kConFab Investigators; Australian Ovarian Cancer Study Group; Wu, AH; Van den Berg, D; Tseng, C-C; Lambrechts, D; Smeets, D; Neven, P; Wildiers, H; Chang-Claude, J; Rudolph, A; Nickels, S; Flesch-Janys, D; Radice, P; Peterlongo, P; Bonanni, B; Pensotti, V; Couch, FJ; Olson, JE; Wang, X; Fredericksen, Z; Pankratz, VS; Giles, GG; Severi, G; Baglietto, L; Haiman, C; Simard, J; Goldberg, MS; Labrèche, F; Dumont, M; Soucy, P; Teo, S; Yip, CH; Phuah, SY; Cornes, BK; Kristensen, VN; Grenaker Alnæs, G; Børresen-Dale, A-L; Zheng, W; Winqvist, R; Pylkäs, K; Jukkola-Vuorinen, A; Grip, M; Andrulis, IL; Knight, JA; Glendon, G; Mulligan, AM; Devillee, P; Figueroa, J; Chanock, SJ; Lissowska, J; Sherman, ME; Hall, P; Schoof, N; Hooning, M; Hollestelle, A; Oldenburg, RA; Tilanus-Linthorst, M; Liu, J; Cox, A; Brock, IW; Reed, MWR; Cross, SS; Blot, W; Signorello, LB; Pharoah, PDP; Dunning, AM; Shah, M; Kang, D; Noh, D-Y; Park, SK; Choi, J-Y; Hartman, M; Miao, H; Lim, WY; Tang, A; Hamann, U; Försti, A; Rüdiger, T; Ulmer, HU; Jakubowska, A; Lubinski, J; Jaworska-Bieniek, K; Durda, K; Sangrajrang, S; Gaborieau, V; Brennan, P; McKay, J; Slager, S; Toland, AE; Vachon, C; Yannoukakos, D; Shen, C-Y; Yu, J-C; Huang, C-S; Hou, M-F; González-Neira, A; Tessier, DC; Vincent, D; Bacot, F; Luccarini, C; Dennis, J; Michailidou, K; Bolla, MK; Wang, J; Easton, DF; García-Closas, M; Dowsett, M; Ashworth, A; Swerdlow, AJ; Peto, J; dos Santos Silva, I; Fletcher, O (2014-05-26)
      INTRODUCTION:We have previously shown that a tag single nucleotide polymorphism (rs10235235), which maps to the CYP3A locus (7q22.1), was associated with a reduction in premenopausal urinary estrone glucuronide levels and ...