Browsing ICR Divisions by author "Leach, Martin"
Now showing items 41-46 of 46
-
T2-Weighted 4D Magnetic Resonance Imaging for Application in Magnetic Resonance-Guided Radiotherapy Treatment Planning.
Freedman, JN; Collins, DJ; Bainbridge, H; Rank, CM; Nill, S; et al. (LIPPINCOTT WILLIAMS & WILKINS, 2017-10-01)OBJECTIVES: The aim of this study was to develop and verify a method to obtain good temporal resolution T2-weighted 4-dimensional (4D-T2w) magnetic resonance imaging (MRI) by using motion information from T1-weighted 4D ... -
The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate-Lactate Exchange in BRAF-Mutant Human Melanoma Cells.
Delgado-Goni, T; Miniotis, MF; Wantuch, S; Parkes, HG; Marais, R; et al. (AMER ASSOC CANCER RESEARCH, 2016-12-01)Understanding the impact of BRAF signaling inhibition in human melanoma on key disease mechanisms is important for developing biomarkers of therapeutic response and combination strategies to improve long-term disease ... -
Time-resolved angiography with stochastic trajectories for dynamic contrast-enhanced MRI in head and neck cancer: Are pharmacokinetic parameters affected?
Panek, R; Schmidt, MA; Borri, M; Koh, D-M; Riddell, A; et al. (WILEY, 2016-11-01)PURPOSE: To investigate the effects of different time-resolved angiography with stochastic trajectories (TWIST) k-space undersampling schemes on calculated pharmacokinetic dynamic contrast-enhanced (DCE) vascular parameters. ... -
Utility of Multi-Parametric Quantitative Magnetic Resonance Imaging for Characterization and Radiotherapy Response Assessment in Soft-Tissue Sarcomas and Correlation With Histopathology.
Winfield, JM; Miah, AB; Strauss, D; Thway, K; Collins, DJ; et al. (FRONTIERS MEDIA SA, 2019-04-25)Purpose: To evaluate repeatability of quantitative multi-parametric MRI in retroperitoneal sarcomas, assess parameter changes with radiotherapy, and correlate pre-operative values with histopathological findings in the ... -
Validating a robust double-quantum-filtered (1) H MRS lactate measurement method in high-grade brain tumours.
Payne, GS; Harris, LM; Cairns, GS; Messiou, C; deSouza, NM; et al. (WILEY-BLACKWELL, 2016-10-01)(1) H MRS measurements of lactate are often confounded by overlapping lipid signals. Double-quantum (DQ) filtering eliminates lipid signals and permits single-shot measurements, which avoid subtraction artefacts in moving ... -
Volume of Bone Metastasis Assessed with Whole-Body Diffusion-weighted Imaging Is Associated with Overall Survival in Metastatic Castration-resistant Prostate Cancer.
Perez-Lopez, R; Lorente, D; Blackledge, MD; Collins, DJ; Mateo, J; et al. (RADIOLOGICAL SOC NORTH AMERICA, 2016-07-01)Purpose To determine the correlation between the volume of bone metastasis as assessed with diffusion-weighted (DW) imaging and established prognostic factors in metastatic castration-resistant prostate cancer (mCRPC) and ...