Browsing ICR Divisions by publication type "Chapter"
Now showing items 1-6 of 6
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EGFR signaling in invasion, angiogenesis and metastasis
(Humana Press, 2008-09-25)Tumour invasion and metastasis are the hallmarks of advanced stage cancer and are associated with poor patient prognosis. EGFR is overexpressed in a variety of tumour types and this frequently correlates with a more ... -
ExPLOITATION OF THE FOLATE RECEPTOR IN THE MANAGEMENT OF CANCER AND INFLAMMATORY DISEASE
(ELSEVIER ACADEMIC PRESS INC, 2008)Over the last 25+ years, the folate receptor (FR) has emerged as an attractive tumor biomarker with the potential to be exploited for therapeutic purposes. Increasing evidence suggests that this enclocytosing protein can ... -
Integration of RNAi and Small Molecule Screens to Identify Targets for Drug Development.
(2019-01)Cellular models for siRNA and small molecule high-throughput screening have been widely used in the last decade to identify targets for drug discovery. As an example, we present a twofold readout approach based on cell ... -
ISBN 978-3-030-11391-9
(Springer, 2019-03-01) -
Structure, function, and mechanism of the Hsp90 molecular chaperone
(ACADEMIC PRESS INC, 2002) -
Utilizing the Luminex Magnetic Bead-Based Suspension Array for Rapid Multiplexed Phosphoprotein Quantification.
(2017-01)The study of protein phosphorylation is critical for the advancement of our understanding of cellular responses to external and internal stimuli. Phosphorylation, the addition of phosphate groups, most often occurs on ...
