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PET/MRI in Oncological Imaging: State of the Art.
(MDPI AG, 2015-07-21)
Positron emission tomography (PET) combined with magnetic resonance imaging (MRI) is a hybrid technology which has recently gained interest as a potential cancer imaging tool. Compared with CT, MRI is advantageous due to ...
RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers.
(AMER ASSOC CANCER RESEARCH, 2017-03-01)
Cancer cells tend to metastasize first to tumor-draining lymph nodes, but the mechanisms mediating cancer cell invasion into the lymphatic vasculature remain little understood. Here, we show that in the human breast tumor ...
Objective, Quantitative, Data-Driven Assessment of Chemical Probes.
(CELL PRESS, 2018-02-15)
Chemical probes are essential tools for understanding biological systems and for target validation, yet selecting probes for biomedical research is rarely based on objective assessment of all potential compounds. Here, we ...
HECTD3 Mediates an HSP90-Dependent Degradation Pathway for Protein Kinase Clients
(Elsevier BV, 2017-06-01)
Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System
(Elsevier BV, 2017-10-01)
The effects of segmentation algorithms on the measurement of 18F-FDG PET texture parameters in non-small cell lung cancer.
(Springer Science and Business Media LLC, 2017-12-01)
BACKGROUND: Measures of tumour heterogeneity derived from 18-fluoro-2-deoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scans are increasingly reported as potential biomarkers of non-small cell ...
An Incidental Renal Oncocytoma: 18F-Choline PET/MRI
(MDPI AG, 2016-04-06)
Young adults: a unique group in cancer epidemiological research.
(ELSEVIER SCIENCE INC, 2018-02-01)
Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C).
(ROYAL SOC, 2017-11-01)
The anaphase promoting complex or cyclosome (APC/C) is a large multi-subunit E3 ubiquitin ligase that orchestrates cell cycle progression by mediating the degradation of important cell cycle regulators. During the two ...
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
(NATURE PUBLISHING GROUP, 2017-11-27)
Vps34 PI3K is thought to be the main producer of phosphatidylinositol-3-monophosphate, a lipid that controls intracellular vesicular trafficking. The organismal impact of systemic inhibition of Vps34 kinase activity is not ...