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Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-x(L)
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2003-05-16)
Glucocorticoids influence many physiological processes, and in particular apoptosis, often with opposite effects depending on the cell type examined. We found that during fibrosarcoma development there is a strong increase ...
A randomised comparison of UK genetic risk counselling services for familial cancer: psychosocial outcomes
(NATURE PUBLISHING GROUP, 2004-08-31)
The aim of the study was to compare psychosocial outcomes for 50 new clinic attendees, referred for cancer genetic counselling to five UK centres. The centres represented England, Scotland and Wales, and were randomly ...
Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer
(2003-12-01)
We report results on risk factors for invasive squamous cell and adenocarcinomas of the cervix in women aged 20-44 years from the UK National Case-Control Study of Cervical Cancer, including 180 women with adenocarcinoma, ...
Heterogeneous proliferative potential in regenerative adult newt cardiomyocytes.
(COMPANY BIOLOGISTS LTD, 2003-10-01)
Adult newt cardiomyocytes, in contrast to their mammalian counterparts, can proliferate after injury and contribute to the functional regeneration of the heart. In order to understand the mechanisms underlying this plasticity ...
Kaposi’s sarcoma-associated herpesvirus-infected primary effusion lymphoma has a gene expression profile
(2003-09-02)
Kaposi’s sarcoma-associated herpesvirus is associated with three human tumors: Kaposi’s sarcoma, and the B cell lymphomas, plasmablastic lymphoma associated with multicentric Castleman’s disease, and primary effusion ...
Variation in RNA expression and genomic DNA content acquired during cell culture
(NATURE PUBLISHING GROUP, 2004-02-26)
Specific chromosomal abnormalities are increasingly recognised to be associated with particular tumour subtypes. These cytogenetic abnormalities define the sites of specific genes, the alteration of which is implicated in ...
Resveratrol inhibits benzo[a]pyrene-DNA adduct formation in human bronchial epithelial cells
(NATURE PUBLISHING GROUP, 2004-07-19)
Resveratrol ( trans-3,4’,5-trihydroxystilbene), a phytoalexin present in various plants and foods, has in several in vitro and in vivo studies demonstrated cancer chemopreventive and chemotherapeutic potential. We investigated ...
Randomised controlled trial of mammographic screening in women from age 40: predicted mortality based on surrogate outcome measures
(NATURE PUBLISHING GROUP, 2005-03-14)
A trial in the UK to study the effect on mortality from breast cancer of invitation for annual mammography from the age of 40-41, has randomised a total of 160 921 women in the ratio 1 : 2 to the intervention and control ...
Should women under 50 be screened for breast cancer?
(NATURE PUBLISHING GROUP, 2004-08-02)
Despite some controversy in recent years, the majority of experts agree on the evidence for effectiveness of breast screening by mammography for women aged 50 years and above, but for those under 50 years, the picture is ...
The psychological impact of human papillomavirus testing in women with borderline or mildly dyskaryotic cervical smear test results: 6-month follow-up
(NATURE PUBLISHING GROUP, 2005-03-28)
State anxiety (S-STAI-6), distress (GHQ-12), concern and quality of life (EuroQoL-EQ-5D) 6 months after human papillomavirus (HPV) testing in women with borderline or mildly dyskaryotic smear test results were assessed ...