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DCE-MRI, DW-MRI, and MRS in Cancer: Challenges and Advantages of Implementing Qualitative and Quantitative Multi-parametric Imaging in the Clinic.

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Publication Date
2016-10
ICR Author
Payne, Geoffrey
deSouza, Nandita
Winfield, Jessica
Author
Winfield, JM
Payne, GS
Weller, A
deSouza, NM
Type
Journal Article
Metadata
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Abstract
Multi-parametric magnetic resonance imaging (mpMRI) offers a unique insight into tumor biology by combining functional MRI techniques that inform on cellularity (diffusion-weighted MRI), vascular properties (dynamic contrast-enhanced MRI), and metabolites (magnetic resonance spectroscopy) and has scope to provide valuable information for prognostication and response assessment. Challenges in the application of mpMRI in the clinic include the technical considerations in acquiring good quality functional MRI data, development of robust techniques for analysis, and clinical interpretation of the results. This article summarizes the technical challenges in acquisition and analysis of multi-parametric MRI data before reviewing the key applications of multi-parametric MRI in clinical research and practice.
URL
https://repository.icr.ac.uk/handle/internal/227
Collections
  • Radiotherapy and Imaging
Licenseref URL
https://creativecommons.org/licenses/by/4.0
Version of record
10.1097/rmr.0000000000000103
Subject
Prostate
Humans
Neoplasms
Magnetic Resonance Imaging
Diffusion Magnetic Resonance Imaging
Reproducibility of Results
Ambulatory Care Facilities
Male
Research team
Magnetic Resonance
Language
eng
License start date
2016-10
Citation
Topics in magnetic resonance imaging : TMRI, 2016, 25 (5), pp. 245 - 254

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