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dc.contributor.authorGalluzzi, L
dc.contributor.authorVitale, I
dc.contributor.authorAaronson, SA
dc.contributor.authorAbrams, JM
dc.contributor.authorAdam, D
dc.contributor.authorAgostinis, P
dc.contributor.authorAlnemri, ES
dc.contributor.authorAltucci, L
dc.contributor.authorAmelio, I
dc.contributor.authorAndrews, DW
dc.contributor.authorAnnicchiarico-Petruzzelli, M
dc.contributor.authorAntonov, AV
dc.contributor.authorArama, E
dc.contributor.authorBaehrecke, EH
dc.contributor.authorBarlev, NA
dc.contributor.authorBazan, NG
dc.contributor.authorBernassola, F
dc.contributor.authorBertrand, MJM
dc.contributor.authorBianchi, K
dc.contributor.authorBlagosklonny, MV
dc.contributor.authorBlomgren, K
dc.contributor.authorBorner, C
dc.contributor.authorBoya, P
dc.contributor.authorBrenner, C
dc.contributor.authorCampanella, M
dc.contributor.authorCandi, E
dc.contributor.authorCarmona-Gutierrez, D
dc.contributor.authorCecconi, F
dc.contributor.authorChan, FK-M
dc.contributor.authorChandel, NS
dc.contributor.authorCheng, EH
dc.contributor.authorChipuk, JE
dc.contributor.authorCidlowski, JA
dc.contributor.authorCiechanover, A
dc.contributor.authorCohen, GM
dc.contributor.authorConrad, M
dc.contributor.authorCubillos-Ruiz, JR
dc.contributor.authorCzabotar, PE
dc.contributor.authorD'Angiolella, V
dc.contributor.authorDawson, TM
dc.contributor.authorDawson, VL
dc.contributor.authorDe Laurenzi, V
dc.contributor.authorDe Maria, R
dc.contributor.authorDebatin, K-M
dc.contributor.authorDeBerardinis, RJ
dc.contributor.authorDeshmukh, M
dc.contributor.authorDi Daniele, N
dc.contributor.authorDi Virgilio, F
dc.contributor.authorDixit, VM
dc.contributor.authorDixon, SJ
dc.contributor.authorDuckett, CS
dc.contributor.authorDynlacht, BD
dc.contributor.authorEl-Deiry, WS
dc.contributor.authorElrod, JW
dc.contributor.authorFimia, GM
dc.contributor.authorFulda, S
dc.contributor.authorGarcía-Sáez, AJ
dc.contributor.authorGarg, AD
dc.contributor.authorGarrido, C
dc.contributor.authorGavathiotis, E
dc.contributor.authorGolstein, P
dc.contributor.authorGottlieb, E
dc.contributor.authorGreen, DR
dc.contributor.authorGreene, LA
dc.contributor.authorGronemeyer, H
dc.contributor.authorGross, A
dc.contributor.authorHajnoczky, G
dc.contributor.authorHardwick, JM
dc.contributor.authorHarris, IS
dc.contributor.authorHengartner, MO
dc.contributor.authorHetz, C
dc.contributor.authorIchijo, H
dc.contributor.authorJäättelä, M
dc.contributor.authorJoseph, B
dc.contributor.authorJost, PJ
dc.contributor.authorJuin, PP
dc.contributor.authorKaiser, WJ
dc.contributor.authorKarin, M
dc.contributor.authorKaufmann, T
dc.contributor.authorKepp, O
dc.contributor.authorKimchi, A
dc.contributor.authorKitsis, RN
dc.contributor.authorKlionsky, DJ
dc.contributor.authorKnight, RA
dc.contributor.authorKumar, S
dc.contributor.authorLee, SW
dc.contributor.authorLemasters, JJ
dc.contributor.authorLevine, B
dc.contributor.authorLinkermann, A
dc.contributor.authorLipton, SA
dc.contributor.authorLockshin, RA
dc.contributor.authorLópez-Otín, C
dc.contributor.authorLowe, SW
dc.contributor.authorLuedde, T
dc.contributor.authorLugli, E
dc.contributor.authorMacFarlane, M
dc.contributor.authorMadeo, F
dc.contributor.authorMalewicz, M
dc.contributor.authorMalorni, W
dc.contributor.authorManic, G
dc.contributor.authorMarine, J-C
dc.contributor.authorMartin, SJ
dc.contributor.authorMartinou, J-C
dc.contributor.authorMedema, JP
dc.contributor.authorMehlen, P
dc.contributor.authorMeier, P
dc.contributor.authorMelino, S
dc.contributor.authorMiao, EA
dc.contributor.authorMolkentin, JD
dc.contributor.authorMoll, UM
dc.contributor.authorMuñoz-Pinedo, C
dc.contributor.authorNagata, S
dc.contributor.authorNuñez, G
dc.contributor.authorOberst, A
dc.contributor.authorOren, M
dc.contributor.authorOverholtzer, M
dc.contributor.authorPagano, M
dc.contributor.authorPanaretakis, T
dc.contributor.authorPasparakis, M
dc.contributor.authorPenninger, JM
dc.contributor.authorPereira, DM
dc.contributor.authorPervaiz, S
dc.contributor.authorPeter, ME
dc.contributor.authorPiacentini, M
dc.contributor.authorPinton, P
dc.contributor.authorPrehn, JHM
dc.contributor.authorPuthalakath, H
dc.contributor.authorRabinovich, GA
dc.contributor.authorRehm, M
dc.contributor.authorRizzuto, R
dc.contributor.authorRodrigues, CMP
dc.contributor.authorRubinsztein, DC
dc.contributor.authorRudel, T
dc.contributor.authorRyan, KM
dc.contributor.authorSayan, E
dc.contributor.authorScorrano, L
dc.contributor.authorShao, F
dc.contributor.authorShi, Y
dc.contributor.authorSilke, J
dc.contributor.authorSimon, H-U
dc.contributor.authorSistigu, A
dc.contributor.authorStockwell, BR
dc.contributor.authorStrasser, A
dc.contributor.authorSzabadkai, G
dc.contributor.authorTait, SWG
dc.contributor.authorTang, D
dc.contributor.authorTavernarakis, N
dc.contributor.authorThorburn, A
dc.contributor.authorTsujimoto, Y
dc.contributor.authorTurk, B
dc.contributor.authorVanden Berghe, T
dc.contributor.authorVandenabeele, P
dc.contributor.authorVander Heiden, MG
dc.contributor.authorVillunger, A
dc.contributor.authorVirgin, HW
dc.contributor.authorVousden, KH
dc.contributor.authorVucic, D
dc.contributor.authorWagner, EF
dc.contributor.authorWalczak, H
dc.contributor.authorWallach, D
dc.contributor.authorWang, Y
dc.contributor.authorWells, JA
dc.contributor.authorWood, W
dc.contributor.authorYuan, J
dc.contributor.authorZakeri, Z
dc.contributor.authorZhivotovsky, B
dc.contributor.authorZitvogel, L
dc.contributor.authorMelino, G
dc.contributor.authorKroemer, G
dc.date.accessioned2018-08-21T10:22:27Z
dc.date.issued2018-03-01
dc.identifier.citationCell death and differentiation, 2018, 25 (3), pp. 486 - 541
dc.identifier.issn1350-9047
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2359
dc.identifier.eissn1476-5403
dc.identifier.doi10.1038/s41418-017-0012-4
dc.description.abstractOver the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field.
dc.formatPrint-Electronic
dc.format.extent486 - 541
dc.languageeng
dc.language.isoeng
dc.publisherNATURE PUBLISHING GROUP
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectLysosomes
dc.subjectAnimals
dc.subjectHumans
dc.subjectNecrosis
dc.subjectMitochondrial Membrane Transport Proteins
dc.subjectCell Death
dc.subjectMitochondrial Permeability Transition Pore
dc.titleMolecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
dc.typeJournal Article
dcterms.dateAccepted2017-10-13
rioxxterms.versionofrecord10.1038/s41418-017-0012-4
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-sa/4.0
rioxxterms.licenseref.startdate2018-03
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfCell death and differentiation
pubs.issue3
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Breast Cancer Research
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Breast Cancer Research/Cell Death and Immunity
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Breast Cancer Research
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Breast Cancer Research/Cell Death and Immunity
pubs.publication-statusPublished
pubs.volume25
pubs.embargo.termsNot known
icr.researchteamCell Death and Immunity
dc.contributor.icrauthorMeier, Pascal


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