dc.contributor.author | Galluzzi, L | |
dc.contributor.author | Vitale, I | |
dc.contributor.author | Aaronson, SA | |
dc.contributor.author | Abrams, JM | |
dc.contributor.author | Adam, D | |
dc.contributor.author | Agostinis, P | |
dc.contributor.author | Alnemri, ES | |
dc.contributor.author | Altucci, L | |
dc.contributor.author | Amelio, I | |
dc.contributor.author | Andrews, DW | |
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dc.contributor.author | Antonov, AV | |
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dc.contributor.author | Baehrecke, EH | |
dc.contributor.author | Barlev, NA | |
dc.contributor.author | Bazan, NG | |
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dc.contributor.author | Bertrand, MJM | |
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dc.contributor.author | Blagosklonny, MV | |
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dc.contributor.author | Candi, E | |
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dc.contributor.author | Cubillos-Ruiz, JR | |
dc.contributor.author | Czabotar, PE | |
dc.contributor.author | D'Angiolella, V | |
dc.contributor.author | Dawson, TM | |
dc.contributor.author | Dawson, VL | |
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dc.contributor.author | DeBerardinis, RJ | |
dc.contributor.author | Deshmukh, M | |
dc.contributor.author | Di Daniele, N | |
dc.contributor.author | Di Virgilio, F | |
dc.contributor.author | Dixit, VM | |
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dc.contributor.author | Duckett, CS | |
dc.contributor.author | Dynlacht, BD | |
dc.contributor.author | El-Deiry, WS | |
dc.contributor.author | Elrod, JW | |
dc.contributor.author | Fimia, GM | |
dc.contributor.author | Fulda, S | |
dc.contributor.author | García-Sáez, AJ | |
dc.contributor.author | Garg, AD | |
dc.contributor.author | Garrido, C | |
dc.contributor.author | Gavathiotis, E | |
dc.contributor.author | Golstein, P | |
dc.contributor.author | Gottlieb, E | |
dc.contributor.author | Green, DR | |
dc.contributor.author | Greene, LA | |
dc.contributor.author | Gronemeyer, H | |
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dc.contributor.author | Hardwick, JM | |
dc.contributor.author | Harris, IS | |
dc.contributor.author | Hengartner, MO | |
dc.contributor.author | Hetz, C | |
dc.contributor.author | Ichijo, H | |
dc.contributor.author | Jäättelä, M | |
dc.contributor.author | Joseph, B | |
dc.contributor.author | Jost, PJ | |
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dc.contributor.author | Rodrigues, CMP | |
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dc.contributor.author | Ryan, KM | |
dc.contributor.author | Sayan, E | |
dc.contributor.author | Scorrano, L | |
dc.contributor.author | Shao, F | |
dc.contributor.author | Shi, Y | |
dc.contributor.author | Silke, J | |
dc.contributor.author | Simon, H-U | |
dc.contributor.author | Sistigu, A | |
dc.contributor.author | Stockwell, BR | |
dc.contributor.author | Strasser, A | |
dc.contributor.author | Szabadkai, G | |
dc.contributor.author | Tait, SWG | |
dc.contributor.author | Tang, D | |
dc.contributor.author | Tavernarakis, N | |
dc.contributor.author | Thorburn, A | |
dc.contributor.author | Tsujimoto, Y | |
dc.contributor.author | Turk, B | |
dc.contributor.author | Vanden Berghe, T | |
dc.contributor.author | Vandenabeele, P | |
dc.contributor.author | Vander Heiden, MG | |
dc.contributor.author | Villunger, A | |
dc.contributor.author | Virgin, HW | |
dc.contributor.author | Vousden, KH | |
dc.contributor.author | Vucic, D | |
dc.contributor.author | Wagner, EF | |
dc.contributor.author | Walczak, H | |
dc.contributor.author | Wallach, D | |
dc.contributor.author | Wang, Y | |
dc.contributor.author | Wells, JA | |
dc.contributor.author | Wood, W | |
dc.contributor.author | Yuan, J | |
dc.contributor.author | Zakeri, Z | |
dc.contributor.author | Zhivotovsky, B | |
dc.contributor.author | Zitvogel, L | |
dc.contributor.author | Melino, G | |
dc.contributor.author | Kroemer, G | |
dc.date.accessioned | 2018-08-21T10:22:27Z | |
dc.date.issued | 2018-03-01 | |
dc.identifier.citation | Cell death and differentiation, 2018, 25 (3), pp. 486 - 541 | |
dc.identifier.issn | 1350-9047 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/2359 | |
dc.identifier.eissn | 1476-5403 | |
dc.identifier.doi | 10.1038/s41418-017-0012-4 | |
dc.description.abstract | Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field. | |
dc.format | Print-Electronic | |
dc.format.extent | 486 - 541 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | NATURE PUBLISHING GROUP | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
dc.subject | Lysosomes | |
dc.subject | Animals | |
dc.subject | Humans | |
dc.subject | Necrosis | |
dc.subject | Mitochondrial Membrane Transport Proteins | |
dc.subject | Cell Death | |
dc.subject | Mitochondrial Permeability Transition Pore | |
dc.title | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2017-10-13 | |
rioxxterms.versionofrecord | 10.1038/s41418-017-0012-4 | |
rioxxterms.licenseref.uri | https://creativecommons.org/licenses/by-nc-sa/4.0 | |
rioxxterms.licenseref.startdate | 2018-03 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | Cell death and differentiation | |
pubs.issue | 3 | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Breast Cancer Research | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Breast Cancer Research/Cell Death and Immunity | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Breast Cancer Research | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Breast Cancer Research/Cell Death and Immunity | |
pubs.publication-status | Published | |
pubs.volume | 25 | |
pubs.embargo.terms | Not known | |
icr.researchteam | Cell Death and Immunity | |
dc.contributor.icrauthor | Meier, Pascal | |