Browsing Cancer Biology by author "Morris, Edward"
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Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase.
Coster, G; Frigola, J; Beuron, F; Morris, EP; Diffley, JFX (CELL PRESS, 2014-09-04)Loading of the six related Minichromosome Maintenance (MCM) proteins as head-to-head double hexamers during DNA replication origin licensing is crucial for ensuring once-per-cell-cycle DNA replication in eukaryotic cells. ...