Browsing Cancer Biology by author "Alfieri, Claudio"
Now showing items 1-2 of 2
-
Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Wan, MSM; Muhammad, R; Koliopoulos, MG; Roumeliotis, TI; Choudhary, JS; et al. (NATURE PORTFOLIO, 2023-05-03)Lysine acetylation in histone tails is a key post-translational modification that controls transcription activation. Histone deacetylase complexes remove histone acetylation, thereby repressing transcription and regulating ... -
Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling.
Koliopoulos, MG; Muhammad, R; Roumeliotis, TI; Beuron, F; Choudhary, JS; et al. (NATURE PORTFOLIO, 2022-08-29)Genes encoding the core cell cycle machinery are transcriptionally regulated by the MuvB family of protein complexes in a cell cycle-specific manner. Complexes of MuvB with the transcription factors B-MYB and FOXM1 activate ...