Browsing Cancer Biology by author "Behrens, Axel"

Now showing items 1-4 of 4

    • Antibodies against endogenous retroviruses promote lung cancer immunotherapy. 

      Ng, KW; Boumelha, J; Enfield, KSS; Almagro, J; Cha, H; et al. (NATURE PORTFOLIO, 2023-04-20)
      B cells are frequently found in the margins of solid tumours as organized follicles in ectopic lymphoid organs called tertiary lymphoid structures (TLS)1,2. Although TLS have been found to correlate with improved patient ...

    • ATMIN Is a Tumor Suppressor Gene in Lung Adenocarcinoma. 

      Foster, H; Ruiz, EJ; Moore, C; Stamp, GWH; Nye, EL; et al. (AMER ASSOC CANCER RESEARCH, 2019-10-15)
      Tumor cells proliferate rapidly and thus are frequently subjected to replication stress and the risk of incomplete duplication of the genome. Fragile sites are replicated late, making them more vulnerable to damage when ...

    • JunD, not c-Jun, is the AP-1 transcription factor required for Ras-induced lung cancer. 

      Ruiz, EJ; Lan, L; Diefenbacher, ME; Riising, EM; Da Costa, C; et al. (AMER SOC CLINICAL INVESTIGATION INC, 2021-07-08)
      The AP-1 transcription factor c-Jun is required for Ras-driven tumorigenesis in many tissues and is considered as a classical proto-oncogene. To determine the requirement for c-Jun in a mouse model of K-RasG12D-induced ...

    • Micro-CT acquisition and image processing to track and characterize pulmonary nodules in mice. 

      Zaw Thin, M; Moore, C; Snoeks, T; Kalber, T; Downward, J; et al. (NATURE PORTFOLIO, 2022-12-09)
      X-ray computed tomography is a reliable technique for the detection and longitudinal monitoring of pulmonary nodules. In preclinical stages of diagnostic or therapeutic development, the miniaturized versions of the clinical ...