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Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures.
(NATURE PUBLISHING GROUP, 2019-08-02)
Visualization of specific organelles in tissues over background fluorescence can be challenging, especially when reporters localize to multiple structures. Instead of trying to identify proteins enriched in specific ...
Proteomic navigation using proximity-labeling.
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019-07-15)
The identification of bona fide protein-protein interactions and the mapping of proteomes was greatly enhanced by protein tagging for generic affinity purification methods and analysis by mass spectrometry (AP-MS). The ...