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Regulators of male and female sexual development are critical for the transmission of a malaria parasite.
(CELL PRESS, 2023-02-08)
Malaria transmission to mosquitoes requires a developmental switch in asexually dividing blood-stage parasites to sexual reproduction. In Plasmodium berghei, the transcription factor AP2-G is required and sufficient for ...
Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110 alpha
(NATURE PORTFOLIO, 2023-02-02)
<jats:title>Abstract</jats:title><jats:p>P110α is a member of the phosphoinositide 3-kinase (PI3K) enzyme family that functions downstream of RAS. RAS proteins contribute to the activation of p110α by interacting directly ...