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dc.contributor.authorAldape, Ken_US
dc.contributor.authorBrindle, KMen_US
dc.contributor.authorChesler, Len_US
dc.contributor.authorChopra, Ren_US
dc.contributor.authorGajjar, Aen_US
dc.contributor.authorGilbert, MRen_US
dc.contributor.authorGottardo, Nen_US
dc.contributor.authorGutmann, DHen_US
dc.contributor.authorHargrave, Den_US
dc.contributor.authorHolland, ECen_US
dc.contributor.authorJones, DTWen_US
dc.contributor.authorJoyce, JAen_US
dc.contributor.authorKearns, Pen_US
dc.contributor.authorKieran, MWen_US
dc.contributor.authorMellinghoff, IKen_US
dc.contributor.authorMerchant, Men_US
dc.contributor.authorPfister, SMen_US
dc.contributor.authorPollard, SMen_US
dc.contributor.authorRamaswamy, Ven_US
dc.contributor.authorRich, JNen_US
dc.contributor.authorRobinson, GWen_US
dc.contributor.authorRowitch, DHen_US
dc.contributor.authorSampson, JHen_US
dc.contributor.authorTaylor, MDen_US
dc.contributor.authorWorkman, Pen_US
dc.contributor.authorGilbertson, RJen_US
dc.coverage.spatialEnglanden_US
dc.date.accessioned2019-03-04T15:47:58Z
dc.date.issued2019-02-07en_US
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/30733593en_US
dc.identifier10.1038/s41571-019-0177-5en_US
dc.identifier.citationNat Rev Clin Oncol, 2019en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3130
dc.identifier.eissn1759-4782en_US
dc.identifier.doi10.1038/s41571-019-0177-5en_US
dc.description.abstractDespite decades of research, brain tumours remain among the deadliest of all forms of cancer. The ability of these tumours to resist almost all conventional and novel treatments relates, in part, to the unique cell-intrinsic and microenvironmental properties of neural tissues. In an attempt to encourage progress in our understanding and ability to successfully treat patients with brain tumours, Cancer Research UK convened an international panel of clinicians and laboratory-based scientists to identify challenges that must be overcome if we are to cure all patients with a brain tumour. The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment.en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.titleChallenges to curing primary brain tumours.en_US
dc.typeJournal Article
rioxxterms.versionofrecord10.1038/s41571-019-0177-5en_US
rioxxterms.licenseref.startdate2019-02-07en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfNat Rev Clin Oncolen_US
pubs.notesNo embargoen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Paediatric Solid Tumour Biology and Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Paediatric Solid Tumour Biology and Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology/Paediatric Solid Tumour Biology and Therapeutics
pubs.publication-statusPublished onlineen_US
pubs.embargo.termsNo embargoen_US
icr.researchteamPaediatric Solid Tumour Biology and Therapeuticsen_US
dc.contributor.icrauthorChesler, Louisen_US
dc.contributor.icrauthorWorkman, Paulen_US


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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/