18F-FDG PET/CT in Detecting Metastatic Infection in Children.

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Date
2016-04
ICR Author
Author
Kouijzer, IJE
Blokhuis, GJ
Draaisma, JMT
Oyen, WJG
de Geus-Oei, L-F
Type
Journal Article
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Abstract
Purpose of the report Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection.Methods The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis.Results FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%.Conclusions FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value.
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https://repository.icr.ac.uk/handle/internal/338
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Subject
Humans
Bacteremia
Fluorodeoxyglucose F18
Radiopharmaceuticals
Positron-Emission Tomography
Tomography, X-Ray Computed
Adolescent
Child
Infant
Female
Male
Multimodal Imaging
Research team
Translational Molecular Imaging
Language
eng
License start date
2016-04
Citation
Clinical nuclear medicine, 2016, 41 (4), pp. 278 - 281