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Class(y) Dissection of <i>BRAF</i> Heterogeneity: Beyond Non-V600.

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Publication Date
2019-12
ICR Author
Valeri, Nicola
Fontana, Elisa
Author
Fontana, E
Valeri, N
Type
Journal Article
Metadata
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Abstract
Different classes of <i>BRAF</i> mutations are present in colorectal and other cancers. Non-V600 mutations are rare; however, their detection rate will increase as the use of next-generation sequencing ramps up quickly in clinical practice. Different biochemical signaling pathways are active in non-V600 <i>BRAF</i>-mutant cancers and may affect treatment response.<i>See related article by Yaeger et al., p. 7089</i>.
URL
https://repository.icr.ac.uk/handle/internal/3422
Collections
  • Molecular Pathology
Licenseref URL
http://www.rioxx.net/licenses/under-embargo-all-rights-reserved
Version of record
10.1158/1078-0432.ccr-19-2732
Subject
Humans
Colonic Neoplasms
Rectal Neoplasms
Proto-Oncogene Proteins B-raf
Mutation
ErbB Receptors
Research team
Gastrointestinal Cancer Biology and Genomics
Systems and Precision Cancer Medicine
Language
eng
Date accepted
2019-10-01
License start date
2019-12
Citation
Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 25 (23), pp. 6896 - 6898

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