Cancer heterogeneity and imaging.
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Date
2017-04-01ICR Author
Author
O'Connor, JPB
Type
Journal Article
Metadata
Show full item recordAbstract
There is interest in identifying and quantifying tumor heterogeneity at the genomic, tissue pathology and clinical imaging scales, as this may help better understand tumor biology and may yield useful biomarkers for guiding therapy-based decision making. This review focuses on the role and value of using x-ray, CT, MRI and PET based imaging methods that identify, measure and map tumor heterogeneity. In particular we highlight the potential value of these techniques and the key challenges required to validate and qualify these biomarkers for clinical use.
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Subject
Humans
Neoplasms
Diagnostic Imaging
Imaging, Three-Dimensional
Genetic Heterogeneity
Image Processing, Computer-Assisted
Biomarkers, Tumor
Research team
Quantitative Biomedical Imaging
Language
eng
Date accepted
2016-10-03
License start date
2017-04
Citation
Seminars in cell & developmental biology, 2017, 64 pp. 48 - 57
Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD