Characterising spatial heterogeneity of multiple myeloma in high resolution by whole body magnetic resonance imaging: Towards macro-phenotype driven patient management.
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Date
2021-01-01ICR Author
Author
Latifoltojar, A
Boyd, K
Riddell, A
Kaiser, M
Messiou, C
Type
Journal Article
Metadata
Show full item recordAbstract
Diagnosis of patients suspected of multiple myeloma requires a combination of serological and biochemical tests, bone marrow aspirate (BMA) and/or bone marrow trephine (BMT) biopsies as well as complementary information provided by whole-body cross-sectional imaging studies. However, given the heterogeneous nature of multiple myeloma, discrepancies can arise between disease burden on trephine and extent of disease within the marrow on whole-body magnetic resonance imaging (WB-MRI). Here, for the first time, we report on a series of symptomatic multiple myeloma patients for whom there was substantial discordance between disease burden on trephine and WB-MRI.
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Research team
Myeloma Group
Language
eng
Date accepted
2020-10-14
License start date
2021-01
Citation
Magnetic resonance imaging, 2021, 75 pp. 60 - 64
Publisher
ELSEVIER SCIENCE INC