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dc.contributor.authorBattisti, NML
dc.contributor.authorLiposits, G
dc.contributor.authorDe Glas, NA
dc.contributor.authorGomes, F
dc.contributor.authorBaldini, C
dc.contributor.authorMohile, S
dc.date.accessioned2021-03-30T10:53:52Z
dc.date.available2021-03-30T10:53:52Z
dc.date.issued2020-07-28
dc.identifier.citationCurrent oncology reports, 2020, 22 (10), pp. 98 - ?en_US
dc.identifier.issn1523-3790
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/4459
dc.identifier.eissn1534-6269en_US
dc.identifier.eissn1534-6269
dc.identifier.doi10.1007/s11912-020-00958-zen_US
dc.identifier.doi10.1007/s11912-020-00958-z
dc.description.abstract<h4>Purpose of review</h4>Decision-making for systemic treatments in older patients with cancer is difficult because of concerns for decreased organ function, risk of toxicity, limited life expectancy due to comorbidities and the lack of evidence available to guide its management in this population. Here, we review the data on the role of systemic agents for the treatment of common malignancies in this age group.<h4>Recent findings</h4>Evidence on the use of systemic treatments for older patients with cancer is increasing, especially for newer options including immune checkpoint inhibitors and targeted agents that provide comparable benefit in older and younger patients. Nonetheless, the risks for short- and long-term toxicities need to be considered. More research is warranted and represents a unique opportunity to increase the knowledge on cancer treatment for older adults. Healthy, older individuals should be considered for standard systemic treatment options, whereas those at risk based on geriatric assessments require adjusted plans. Geriatric assessments are key for decision-making.en_US
dc.formatElectronicen_US
dc.format.extent98 - ?en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_US
dc.titleSystemic Therapy of Common Tumours in Older Patients: Challenges and Opportunities. A Young International Society of Geriatric Oncology Review Paper.en_US
dc.typeJournal Article
dcterms.dateAccepted2020-07-28
rioxxterms.versionAMen_US
rioxxterms.versionofrecord10.1007/s11912-020-00958-zen_US
rioxxterms.licenseref.startdate2020-07-28
dc.relation.isPartOfCurrent oncology reportsen_US
pubs.issue10en_US
pubs.notesNo embargoen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Breast Cancer Research
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Breast Cancer Research/Breast Cancer Clinical Research
pubs.publication-statusPublisheden_US
pubs.volume22en_US
pubs.embargo.termsNo embargoen_US
icr.researchteamBreast Cancer Clinical Research
dc.contributor.icrauthorBattisti, Nicoloen_US


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