Image-guided Adaptive Radiotherapy for Bladder Cancer.
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Date
2021-06-01ICR Author
Author
Kong, V
Hansen, VN
Hafeez, S
Type
Journal Article
Metadata
Show full item recordAbstract
Technological advancement has facilitated patient-specific radiotherapy in bladder cancer. This has been made possible by developments in image-guided radiotherapy (IGRT). Particularly transformative has been the integration of volumetric imaging into the workflow. The ability to visualise the bladder target using cone beam computed tomography and magnetic resonance imaging initially assisted with determining the magnitude of inter- and intra-fraction target change. It has led to greater confidence in ascertaining true anatomy at each fraction. The increased certainty of dose delivered to the bladder has permitted the safe reduction of planning target volume margins. IGRT has therefore improved target coverage with a reduction in integral dose to the surrounding tissue. Use of IGRT to feed back into plan and dose delivery optimisation according to the anatomy of the day has enabled adaptive radiotherapy bladder solutions. Here we undertake a review of the stepwise developments underpinning IGRT and adaptive radiotherapy strategies for external beam bladder cancer radiotherapy. We present the evidence in accordance with the framework for systematic clinical evaluation of technical innovations in radiation oncology (R-IDEAL).
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Research team
Clinical Academic Radiotherapy (Huddart)
Clinical Academic Radiotherapy (Huddart)
Language
eng
Date accepted
2021-03-30
Citation
Clinical oncology (Royal College of Radiologists (Great Britain)), 2021, 33 (6), pp. 350 - 368
Publisher
ELSEVIER SCIENCE LONDON