dc.contributor.author | Harris, E | |
dc.contributor.author | Sinnatamby, R | |
dc.contributor.author | O'Flynn, E | |
dc.contributor.author | Kirby, AM | |
dc.contributor.author | Bamber, JC | |
dc.date.accessioned | 2021-12-16T11:20:49Z | |
dc.date.available | 2021-12-16T11:20:49Z | |
dc.date.issued | 2021-10-01 | |
dc.identifier | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000716923100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4b848928d1c3e5c86d298abb68475f9 | |
dc.identifier | ARTN 9391 | |
dc.identifier.citation | APPLIED SCIENCES-BASEL, 2021, 11 (20), pp. ? - ? (16) | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/4931 | |
dc.identifier.eissn | 2076-3417 | |
dc.identifier.doi | 10.3390/app11209391 | |
dc.description.abstract | <jats:p>Quantitative measures of radiation-induced breast stiffness are required to support clinical studies of novel breast radiotherapy regimens and exploration of personalised therapy, however, variation between shear-wave elastography (SWE) machines may limit the usefulness of shear-wave speed (cs) for this purpose. Mean cs measured in four healthy volunteers’ breasts and a phantom using 2D-SWE machines Acuson S2000 (Siemens Medical Solutions) and Aixplorer (Supersonic Imagine) were compared. Shear-wave speed was measured in the skin region, subcutaneous adipose tissue and parenchyma. cs estimates were on average 2.3% greater when using the Aixplorer compared to S2000 in vitro. In vivo, cs estimates were on average 43.7%, 36.3% and 49.9% significantly greater (p << 0.01) when using the Aixplorer compared to S2000, for skin region, subcutaneous adipose tissue and parenchyma, respectively. In conclusion, despite relatively small differences between machines observed in vitro, large differences in absolute measures of shear wave speed measured were observed in vivo, which may prevent pooling of cross-machine data in clinical studies of the breast.</jats:p> | |
dc.format.extent | ? - ? (16) | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | MDPI | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
dc.subject | Science & Technology | |
dc.subject | Physical Sciences | |
dc.subject | Technology | |
dc.subject | Chemistry, Multidisciplinary | |
dc.subject | Engineering, Multidisciplinary | |
dc.subject | Materials Science, Multidisciplinary | |
dc.subject | Physics, Applied | |
dc.subject | Chemistry | |
dc.subject | Engineering | |
dc.subject | Materials Science | |
dc.subject | Physics | |
dc.subject | shear-wave elastography | |
dc.subject | shear-wave speed | |
dc.subject | radiation-induced breast toxicity | |
dc.subject | tissue stiffness | |
dc.subject | cross-machine comparison | |
dc.subject | 1 BASIC PRINCIPLES | |
dc.subject | ULTRASOUND ELASTOGRAPHY | |
dc.subject | RADIATION FORCE | |
dc.subject | CLINICAL-USE | |
dc.subject | QUANTITATIVE ASSESSMENT | |
dc.subject | EFSUMB GUIDELINES | |
dc.subject | WFUMB GUIDELINES | |
dc.subject | SKIN STIFFNESS | |
dc.subject | RECOMMENDATIONS | |
dc.subject | QUANTIFICATION | |
dc.title | A Cross-Machine Comparison of Shear-Wave Speed Measurements Using 2D Shear-Wave Elastography in the Normal Female Breast | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2021-10-03 | |
rioxxterms.version | VoR | |
rioxxterms.versionofrecord | 10.3390/app11209391 | |
rioxxterms.licenseref.uri | https://creativecommons.org/licenses/by/4.0 | |
rioxxterms.licenseref.startdate | 2021-10-01 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | APPLIED SCIENCES-BASEL | |
pubs.issue | 20 | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Breast Cancer Radiotherapy | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Breast Cancer Radiotherapy/Breast Cancer Radiotherapy (hon.) | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Ultrasound & Optical Imaging | |
pubs.organisational-group | /ICR/Primary Group/Royal Marsden Clinical Units | |
pubs.publication-status | Published | |
pubs.volume | 11 | |
pubs.embargo.terms | Not known | |
icr.researchteam | Breast Cancer Radiotherapy | |
icr.researchteam | Ultrasound & Optical Imaging | |
dc.contributor.icrauthor | Bamber, Jeffrey | |