Browsing Genetics and Epidemiology by author "Ashworth, Alan"
Now showing items 1-4 of 4
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Combined effects of endogenous sex hormone levels and mammographic density on postmenopausal breast cancer risk: results from the Breakthrough Generations Study.
(2014-04)Background Mammographic density and sex hormone levels are strong risk factors for breast cancer, but it is unclear whether they represent the same aetiological entity or are independent risk factors.Methods Within the ... -
Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.
(2014-05-26)Introduction We have previously shown that a tag single nucleotide polymorphism (rs10235235), which maps to the CYP3A locus (7q22.1), was associated with a reduction in premenopausal urinary estrone glucuronide levels and ... -
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
(2013-04)Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ∼9% of the familial risk of the disease. We ... -
Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study.
(2014-02-04)Introduction Breast development and hormonal changes at puberty might affect breast cancer risk, but epidemiological analyses have focussed largely on age at menarche and not at other pubertal stages.Methods We investigated ...
