Browsing Genetics and Epidemiology by author "Elliott, Anna"
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Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour.
Hanks, S; Perdeaux, ER; Seal, S; Ruark, E; Mahamdallie, SS; et al. (NATURE PUBLISHING GROUP, 2014-08-07)Wilms tumour is a childhood kidney cancer. Here we identify inactivating CTR9 mutations in 3 of 35 Wilms tumour families, through exome and Sanger sequencing. By contrast, no similar mutations are present in 1,000 population ...