Browsing Molecular Pathology by author "Tam, Yuen Bun"

Now showing items 1-4 of 4

    • Bcar1/p130Cas is essential for ventricular development and neural crest cell remodelling of the cardiac outflow tract. 

      Mahmoud, M; Evans, I; Wisniewski, L; Tam, Y; Walsh, C; et al. (OXFORD UNIV PRESS, 2022-06-29)
      AIMS: The adapter protein p130Cas, encoded by the Bcar1 gene, is a key regulator of cell movement, adhesion, and cell cycle control in diverse cell types. Bcar1 constitutive knockout mice are embryonic lethal by embryonic ...

    • Molecular profiling in desmoplastic small round cell tumours. 

      Tam, YB; Jones, RL; Huang, PH (PERGAMON-ELSEVIER SCIENCE LTD, 2023-04-01)
      Desmoplastic small round cell tumour (DSRCT) is an ultra-rare soft tissue sarcoma that is characterised by aggressive disease and dismal patient outcomes. Despite multi-modal therapy, prognosis remains poor and there are ...

    • The perplexing role of immuno-oncology drugs in osteosarcoma. 

      Smrke, A; Tam, YB; Anderson, PM; Jones, RL; Huang, PH (ELSEVIER, 2021-12-01)
      Osteosarcoma is a rare, primary tumour of bone. Curative treatment consists of multi-agent chemotherapy and complete surgical resection. Despite the use of multi-agent chemotherapy, the risk of recurrence is high. Survival ...

    • Translational Aspects of Epithelioid Sarcoma: Current Consensus. 

      Grünewald, TGP; Postel-Vinay, S; Nakayama, RT; Berlow, NE; Bolzicco, A; et al. (AMER ASSOC CANCER RESEARCH, 2024-03-15)
      Epithelioid sarcoma (EpS) is an ultra-rare malignant soft-tissue cancer mostly affecting adolescents and young adults. EpS often exhibits an unfavorable clinical course with fatal outcome in ∼50% of cases despite aggressive ...