DAISY: picking synthetic lethals from cancer genomes.
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Date
2014-09-08ICR Author
Author
Ryan, CJ
Lord, CJ
Ashworth, A
Type
Journal Article
Metadata
Show full item recordAbstract
A better understanding of genetic interactions in cancer might help identify new therapeutic approaches that exploit the concept of synthetic lethality. Ruppin and colleagues have developed a new computational method, DAISY, that predicts such interactions and potentially facilitates the delineation and validation of comprehensive genetic interaction networks.
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Subject
Humans
Neoplasms
Computational Biology
Data Mining
Research team
Gene Function
Language
eng
License start date
2014-09
Citation
Cancer cell, 2014, 26 (3), pp. 306 - 308
Publisher
CELL PRESS