Now showing items 1-7 of 7

    • Clinical and immunologic implications of COVID-19 in patients with melanoma and renal cell carcinoma receiving immune checkpoint inhibitors. 

      Switzer, B; Haanen, J; Lorigan, PC; Puzanov, I; Turajlic, S
      The clinical and immunologic implications of the SARS-CoV-2 pandemic for patients with cancer receiving systemic anticancer therapy have introduced a multitude of clinical challenges and academic controversies. This review ...
    • Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2. 

      Au, L; Fendler, A; Shepherd, STC; Rzeniewicz, K; Cerrone, M; Byrne, F; Carlyle, E; Edmonds, K; Del Rosario, L; Shon, J; Haynes, WA; Ward, B; Shum, B; Gordon, W; Gerard, CL; Xie, W; Joharatnam-Hogan, N; Young, K; Pickering, L; Furness, AJS; Larkin, J; Harvey, R; Kassiotis, G; Gandhi, S; Crick COVID-19 Consortium; Swanton, C; Fribbens, C; Wilkinson, KA; Wilkinson, RJ; Lau, DK; Banerjee, S; Starling, N; Chau, I; CAPTURE Consortium; Turajlic, S (2021-05-26)
      Patients with cancer are currently prioritized in coronavirus disease 2019 (COVID-19) vaccination programs globally, which includes administration of mRNA vaccines. Cytokine release syndrome (CRS) has not been reported ...
    • Implications of cancer evolution for drug development. 

      Turajlic, S; Swanton, C (2017-07)
    • Resolving genetic heterogeneity in cancer. 

      Turajlic, S; Sottoriva, A; Graham, T; Swanton, C (2019-07)
      To a large extent, cancer conforms to evolutionary rules defined by the rates at which clones mutate, adapt and grow. Next-generation sequencing has provided a snapshot of the genetic landscape of most cancer types, and ...
    • SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay 

      Buck, MD; Poirier, EZ; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; Byrne, R; Caidan, S; Crawford, M; Cubitt, L; Gandhi, S; Goldstone, R; Grant, PR; Gulati, K; Hindmarsh, S; Howell, M; Hubank, M; Instrell, R; Jiang, M; Kassiotis, G; Lu, W-T; MacRae, JI; Martini, I; Miller, D; Moore, D; Nastouli, E; Nicod, J; Nightingale, L; Olsen, J; Oomatia, A; O'Reilly, N; Rideg, A; Song, O-R; Strange, A; Swanton, C; Turajlic, S; Wu, M; Reis e Sousa, C (F1000 Research Ltd, 2021-01-21)
      <ns3:p>The ongoing pandemic of SARS-CoV-2 calls for rapid and cost-effective methods to accurately identify infected individuals. The vast majority of patient samples is assessed for viral RNA presence by RT-qPCR. Our ...
    • The GENIE Is Out of the Bottle: Landmark Cancer Genomics Dataset Released. 

      Litchfield, K; Turajlic, S; Swanton, C (2017-08)
      <b/> In this issue of <i>Cancer Discovery</i>, an overview of the AACR Project GENIE, a landmark study in cancer genomics, is presented by The AACR Project GENIE Consortium. A summary of the goals and objectives of this ...
    • Tracking the Evolution of Non-Small-Cell Lung Cancer. 

      Jamal-Hanjani, M; Wilson, GA; McGranahan, N; Birkbak, NJ; Watkins, TBK; Veeriah, S; Shafi, S; Johnson, DH; Mitter, R; Rosenthal, R; Salm, M; Horswell, S; Escudero, M; Matthews, N; Rowan, A; Chambers, T; Moore, DA; Turajlic, S; Xu, H; Lee, S-M; Forster, MD; Ahmad, T; Hiley, CT; Abbosh, C; Falzon, M; Borg, E; Marafioti, T; Lawrence, D; Hayward, M; Kolvekar, S; Panagiotopoulos, N; Janes, SM; Thakrar, R; Ahmed, A; Blackhall, F; Summers, Y; Shah, R; Joseph, L; Quinn, AM; Crosbie, PA; Naidu, B; Middleton, G; Langman, G; Trotter, S; Nicolson, M; Remmen, H; Kerr, K; Chetty, M; Gomersall, L; Fennell, DA; Nakas, A; Rathinam, S; Anand, G; Khan, S; Russell, P; Ezhil, V; Ismail, B; Irvin-Sellers, M; Prakash, V; Lester, JF; Kornaszewska, M; Attanoos, R; Adams, H; Davies, H; Dentro, S; Taniere, P; O'Sullivan, B; Lowe, HL; Hartley, JA; Iles, N; Bell, H; Ngai, Y; Shaw, JA; Herrero, J; Szallasi, Z; Schwarz, RF; Stewart, A; Quezada, SA; Le Quesne, J; Van Loo, P; Dive, C; Hackshaw, A; Swanton, C; TRACERx Consortium (2017-06)
      Background Among patients with non-small-cell lung cancer (NSCLC), data on intratumor heterogeneity and cancer genome evolution have been limited to small retrospective cohorts. We wanted to prospectively investigate ...