Browsing Other ICR Research by author "Hughes, David"
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Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap
Botella, JA; Kretzschmar, D; Kiermayer, C; Feldmann, P; Hughes, DA; et al. (2003-01)Ras signaling has been shown to play an important role in promoting cell survival in many different tissues. Here we show that upregulation of Ras activity in adult Drosophila neurons induces neuronal cell death, as evident ...