Now showing items 1-2 of 2

    • Pan-cancer deconvolution of tumour composition using DNA methylation. 

      Chakravarthy, A; Furness, A; Joshi, K; Ghorani, E; Ford, K; et al. (NATURE PUBLISHING GROUP, 2018-08-13)
      The nature and extent of immune cell infiltration into solid tumours are key determinants of therapeutic response. Here, using a DNA methylation-based approach to tumour cell fraction deconvolution, we report the integrated ...
    • Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment. 

      Wong, YNS; Joshi, K; Khetrapal, P; Ismail, M; Reading, JL; et al. (ROCKEFELLER UNIV PRESS, 2018-11-05)
      Despite the advances in cancer immunotherapy, only a fraction of patients with bladder cancer exhibit responses to checkpoint blockade, highlighting a need to better understand drug resistance and identify rational ...