Browsing Other ICR Research by author "Wasti, Ajla"

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    • Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells. 

      Rajagopalan, KN; Egnatchik, RA; Calvaruso, MA; Wasti, AT; Padanad, MS; et al. (Springer Science and Business Media LLC, 2015-01-01)
      BACKGROUND: Pyruvate dehydrogenase (PDH) occupies a central node of intermediary metabolism, converting pyruvate to acetyl-CoA, thus committing carbon derived from glucose to an aerobic fate rather than an anaerobic one. ...