Browsing Other ICR Research by title
Now showing items 619-622 of 622
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Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis.
(OXFORD UNIV PRESS, 2018-08-01)OBJECTIVES: To identify molecular differences between chondrocytes from osteophytic and articular cartilage tissue from OA patients. METHODS: We investigated genes and pathways by combining genome-wide DNA methylation, RNA ... -
Workshop report: the clinical application of data from multiplex assays of variant effect (MAVEs), 12 July 2023.
(SPRINGERNATURE, 2024-05-01)Clinical classification of genomic variants identified on sequencing is often challenging, with many variants classified as Variants of Uncertain Significance (VUS) on account of insufficient evidence. Advances in sequencing ... -
Young oncologists' perspective on the role and future of the clinician-scientist in oncology.
(ELSEVIER, 2023-10-01) -
Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio.
(SPRINGER, 2023-09-01)Actin, tropomyosin and troponin, the proteins that comprise the contractile apparatus of the cardiac thin filament, are highly conserved across species. We have used cryo-EM to study the three-dimensional structure of the ...