Browsing Other ICR Research by author "Tutt, Andrew"
Now showing items 21-25 of 25
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Tandem duplications contribute to not one but two distinct phenotypes.
Watkins, J; Tutt, A; Grigoriadis, A (NATL ACAD SCIENCES, 2016-09-06) -
Targeting folate receptor alpha for cancer treatment.
Cheung, A; Bax, HJ; Josephs, DH; Ilieva, KM; Pellizzari, G; et al. (IMPACT JOURNALS LLC, 2016-08-09)Promising targeted treatments and immunotherapy strategies in oncology and advancements in our understanding of molecular pathways that underpin cancer development have reignited interest in the tumor-associated antigen ... -
TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer.
Beatson, RE; Parente-Pereira, AC; Halim, L; Cozzetto, D; Hull, C; et al. (CELL PRESS, 2021-12-21)Despite its role in cancer surveillance, adoptive immunotherapy using γδ T cells has achieved limited efficacy. To enhance trafficking to bone marrow, circulating Vγ9Vδ2 T cells are expanded in serum-free medium containing ... -
Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer.
Harris, RJ; Cheung, A; Ng, JCF; Laddach, R; Chenoweth, AM; et al. (AMER ASSOC CANCER RESEARCH, 2021-08-15)In breast cancer, humoral immune responses may contribute to clinical outcomes, especially in more immunogenic subtypes. Here, we investigated B lymphocyte subsets, immunoglobulin expression, and clonal features in breast ... -
Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment.
Eisenblaetter, M; Flores-Borja, F; Lee, JJ; Wefers, C; Smith, H; et al. (IVYSPRING INT PUBL, 2017-06-15)Background Systemic cancer spread is preceded by the establishment of a permissive microenvironment in the target tissue of metastasis - the premetastatic niche. As crucial players in establishment of the pre-metastatic ...