Browsing Other ICR Research by title
Now showing items 701-720 of 1002
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Quantifying effects of lead shielding in electron beams: a Monte Carlo study
(IOP PUBLISHING LTD, 2001-03)Lead shielding in contact with the patient’s skin is often encountered in radiotherapy with electron beams. The influence of the lead shielding on dose distributions in the patient cannot fully be assessed using modern ... -
Rabbit endogenous retrovirus-H encodes a functional protease
(2003-01)Recent studies have revealed that ‘human retrovirus-5’ sequences found in human samples belong to a rabbit endogenous retrovirus family named RERV-H. A part of the gag-pro region of the RERV-H genome was amplified by PCR ... -
Radiation response and cure rate of human colon adenocarcinoma spheroids of different size: the significance of hypoxia on tumor control modelling
(2001)Purpose: To evaluate the adequacy of a Poisson tumor control probability (tcp) model and the impact of hypoxia on tumor cure. Methods and Materials: A human colon adenocarcinoma cell line, WiDr, was grown as multicellular ... -
Radiologic progression of glioblastoma under therapy-an exploratory analysis of AVAglio.
(2018-03)Background In this exploratory analysis of AVAglio, a randomized phase III clinical study that investigated the addition of bevacizumab (Bev) to radiotherapy/temozolomide in newly diagnosed glioblastoma, we aim to ... -
Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib: Patient-focused outcome results from the randomised phase III REACH study.
(2017-08)Purpose To report patient-focused outcomes as measured by quality of life (QoL) and performance status (PS) in REACH, a phase III placebo-controlled randomised study, assessing ramucirumab in advanced hepatocellular carcinoma ... -
Ramucirumab as Second-Line Treatment in Patients With Advanced Hepatocellular Carcinoma: Analysis of REACH Trial Results by Child-Pugh Score.
(2017-02)Importance REACH is the first phase 3 trial to provide information on hepatocellular cancer (HCC) in the second-line (postsorafenib) setting categorized by Child-Pugh score, a scoring system used to measure the severity ... -
Randomized, placebo-controlled trial of gastric acid-lowering therapy on duodenal polyposis and relative adduct labeling in familial adenomatous polyposis
(2001-11)PURPOSE: Bile has been implicated in the pathogenesis of duodenal polyps in patients with familial adenomatous polyposis. In vitro experiments have shown that familial adenomatous polyposis bile is capable of producing DNA ... -
Rapid amplification of immunoglobulin heavy chain switch (IGHS) translocation breakpoints using long-distance inverse PCR
(NATURE PUBLISHING GROUP, 2004-12)Molecular cloning of immunoglobulin heavy chain (IGH) translocation breakpoints identifies genes of biological importance in the development of normal and malignant B cells. Long-distance inverse PCR (LDI-PCR) was first ... -
Rapid uropathogen identification using surface enhanced Raman spectroscopy active filters.
(2021-04-22)Urinary tract infection is one of the most common bacterial infections leading to increased morbidity, mortality and societal costs. Current diagnostics exacerbate this problem due to an inability to provide timely pathogen ... -
Rare non-epithelial ovarian neoplasms: Pathology, genetics and treatment.
(2016-07)Rare non-epithelial ovarian neoplasms have posed management challenges for many years. Their rarity means that most specialist practitioners will see one such case every several years, and most generalists may never see a ... -
Re-challenge chemotherapy with gemcitabine plus carboplatin in patients with non-small cell lung cancer.
(2013-10)Despite recent improvements to current therapies and the emergence of novel agents to manage advanced non-small cell lung cancer (NSCLC), the patients' overall survival remains poor. Re-challenging with first-line chemotherapy ... -
Re-irradiation of cervical and endometrial cancer
(Ovid Technologies (Wolters Kluwer Health), 2017-09) -
Real World Evidence: A Quantitative and Qualitative Glance at Participant Feedback from a Free-Response Survey Investigating Experiences of a Structured Exercise Intervention for Men with Prostate Cancer.
(2017-01)Aim To explore patient experiences of a structured exercise intervention for men with prostate cancer (PCa).Sample 41 men with either localised or advanced PCa who had been referred for a structured exercise programme by ... -
Receptor tyrosine kinase mutations in myeloid neoplasms
(BLACKWELL PUBLISHING LTD, 2002-06) -
Recipient/donor HLA and CMV matching in recipients of T-cell-depleted unrelated donor haematopoietic cell transplants.
(2017-05)Improving haematopoietic cell transplantation outcomes by selection of an HLA-matched unrelated donor is best practice; however, donor selection by secondary characteristics is controversial. We studied 1271 recipients ... -
Recognition of polyubiquitin isoforms by the multiple ubiquitin binding modules of isopeptidase T
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2008-07-11)The conjugation of polyubiquitin to target proteins acts as a signal that regulates target stability, localization, and function. Several ubiquitin binding domains have been described, and while much is known about ubiquitin ...
