Now showing items 1002-1002 of 1002

    • Yes-associated protein (YAP) functions as a tumor suppressor in breast 

      Yuan, M; Tomlinson, V; Lara, R; Holliday, D; Chelala, C; Harada, T; Gangeswaran, R; Manson-Bishop, C; Smith, P; Danovi, SA; Pardo, O; Crook, T; Mein, CA; Lemoine, NR; Jones, LJ; Basu, S (NATURE PUBLISHING GROUP, 2008-11)
      Yes-associated protein (YAP) has been shown to positively regulate p53 family members and to be negatively regulated by the AKT proto-oncogene product in promoting apoptosis. On the basis of this function and its location ...