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Occupational, domestic and environmental mesothelioma risks in the British population: a case-control study
(NATURE PUBLISHING GROUP, 2009-03-31)
We obtained lifetime occupational and residential histories by telephone interview with 622 mesothelioma patients (512 men, 110 women) and 1420 population controls. Odds ratios (ORs) were converted to lifetime risk (LR) ...
Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis
(BIOMED CENTRAL LTD, 2009-08)
Background: The availability of the complete chicken (Gallus gallus) genome sequence as well as a large number of chicken probes for fluorescent in-situ hybridization (FISH) and microarray resources facilitate comparative ...
Functional characterization of E- and P-cadherin in invasive breast cancer cells
(BIOMED CENTRAL LTD, 2009-03-03)
Background: Alterations in the cadherin-catenin adhesion complexes are involved in tumor initiation, progression and metastasis. However, the functional implication of distinct cadherin types in breast cancer biology is ...
Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology
(2009)
Background: In recent years RNAi screening has proven a powerful tool for dissecting gene functions in animal cells in culture. However, to date, most RNAi screens have been performed in a single cell line, and results ...
Epstein-Barr Virus Latency in B Cells Leads to Epigenetic Repression and CpG Methylation of the Tumour Suppressor Gene Bim
(PUBLIC LIBRARY SCIENCE, 2009-06)
In human B cells infected with Epstein-Barr virus (EBV), latency-associated virus gene products inhibit expression of the proapoptotic Bcl-2-family member Bim and enhance cell survival. This involves the activities of the ...
High concentrations of reactive oxygen species in the BAL fluid are correlated with lung injury in rabbits after hemorrhagic shock and resuscitation.
(TOHOKU UNIV MEDICAL PRESS, 2009-11-01)
Increased levels of cytokines or reactive oxygen species (ROS) in the bronchoalveolar lavage (BAL) fluid are associated with acute lung injury after ischemia/reperfusion. We investigated the correlation of these markers ...
Reasons of PEG failure to eliminate gastroesophageal reflux in mechanically ventilated patients.
(BAISHIDENG PUBLISHING GROUP INC, 2009-11-21)
AIM: To investigate factors predicting failure of percutaneous endoscopic gastrostomy (PEG) to eliminate gastroesophageal reflux (GER). METHODS: Twenty-nine consecutive mechanically ventilated patients were investigated. ...