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The integration of BRCA testing into oncology clinics.

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Date
2016-06
ICR Author
Rahman, Sabera
Banerjee, Susana
Author
Percival, N
George, A
Gyertson, J
Hamill, M
Fernandes, A
Davies, E
Rahman, N
Banerjee, S
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Type
Journal Article
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Abstract
Purpose The PARP inhibitor, Olaparib, is approved for women with BRCA-mutated ovarian cancer. Therefore there is an urgent need to test patients and obtain results in time to influence treatment. Models of BRCA testing, such as the mainstreaming oncogenetic pathway, involving oncology health professionals are being used. The authors report on the establishment of the extended role of the clinical nurse specialist in consenting women for BRCA testing in routine gynaecology-oncology clinics using the mainstreaming model.Methods Nurses undertook generic consent training and specific counselling training for BRCA testing in the form of a series of online videos, written materials and checklists before obtaining approval to consent patients for germline BRCA1 and BRCA2 mutations.Results Between July 2013 and December 2015, 108 women with ovarian cancer were counselled and consented by nurses in the medical oncology clinics at a single centre (The Royal Marsden, UK). This represented 36% of all ovarian cancer patients offered BRCA testing in the oncology clinics at the centre. Feedback from patients and nurses was encouraging with no significant issues raised in the counselling and consenting process.Conclusion The mainstreaming model allows for greater access to BRCA testing for ovarian cancer patients, many of whom may benefit from personalised therapy (PARP inhibitors). This is the first report of oncology nurses in the BRCA testing pathway. Specialist oncology nurses trained in BRCA testing have an important role within a multidisciplinary team counselling and consenting patients to undergo BRCA testing.
URI
https://repository.icr.ac.uk/handle/internal/184
DOI
https://doi.org/10.12968/bjon.2016.25.12.690
Collections
  • Breast Cancer Research
  • Genetics and Epidemiology
Subject
Humans
Ovarian Neoplasms
Piperazines
Phthalazines
Nurse's Role
Mutation
Genes, BRCA1
Genes, BRCA2
Informed Consent
Nurse Clinicians
Cancer Care Facilities
Patient Satisfaction
Female
Genetic Testing
Hereditary Breast and Ovarian Cancer Syndrome
Oncology Nursing
Poly(ADP-ribose) Polymerase Inhibitors
Precision Medicine
Research team
Genetic Susceptibility
Language
eng
License start date
2016-06
Citation
British journal of nursing (Mark Allen Publishing), 2016, 25 (12), pp. 690 - 694

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