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dc.date.accessioned2018-07-05T10:06:56Z
dc.date.issued2015
dc.identifierhttp://www.hindawi.com/journals/grp/2015/314158/
dc.identifier.citation2015
dc.identifier.issn1687-6121
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/1991
dc.description.abstractCollision tumors are rare neoplasms displaying two distinct cell populations developing in juxtaposition to one another without areas of intermingling. They are rare entities with only 63 cases described in English literature. Tumors encountered are gastric adenocarcinomas colliding with lymphomas, gastrointestinal stromal tumors, squamous cell carcinomas, and neuroendocrine tumors. Their cell origin is obsolete by the time of diagnosis. Different tumorigenesis theories have been suggested to explain their behavior, yet none has managed to provide satisfactory explanation for all cases. Clinically they are indistinguishable from the dominant tumor. Lack of data does not allow detailed assessment of their behavior yet they seem aggressive neoplasms with dismal prognosis. The majority of cases have been diagnosed postoperatively during histologic examination of specimens. There are no guidelines or concrete evidence to support best way of adjuvant or other types of treatment. However, these rare neoplasms might help in unlocking secrets of cancer behavior including tumorigenesis, differentiation, and adhesion and thus clinicians should be aware of their existence.
dc.languageeng
dc.language.isoeng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectGASTROINTESTINAL STROMAL TUMOR PRIMARY MALIGNANT-LYMPHOMA
dc.titleGastric Collision Tumors: An Insight into Their Origin and Clinical Significance
dc.typeOther
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2015
rioxxterms.typeOther
pubs.notesISI Document Delivery No.: CC1SX Times Cited: 0 Cited Reference Count: 58 Michalinos, Adamantios Constantinidou, Anastasia Kontos, Michael 0 HINDAWI PUBLISHING CORPORATION NEW YORK GASTROENT RES PRACT public Collision tumors are rare neoplasms displaying two distinct cell populations developing in juxtaposition to one another without areas of intermingling. They are rare entities with only 63 cases described in English literature. Tumors encountered are gastric adenocarcinomas colliding with lymphomas, gastrointestinal stromal tumors, squamous cell carcinomas, and neuroendocrine tumors. Their cell origin is obsolete by the time of diagnosis. Different tumorigenesis theories have been suggested to explain their behavior, yet none has managed to provide satisfactory explanation for all cases. Clinically they are indistinguishable from the dominant tumor. Lack of data does not allow detailed assessment of their behavior yet they seem aggressive neoplasms with dismal prognosis. The majority of cases have been diagnosed postoperatively during histologic examination of specimens. There are no guidelines or concrete evidence to support best way of adjuvant or other types of treatment. However, these rare neoplasms might help in unlocking secrets of cancer behavior including tumorigenesis, differentiation, and adhesion and thus clinicians should be aware of their existence.
pubs.notesNot known
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pubs.organisational-group/ICR
pubs.embargo.termsNot known
dc.contributor.icrauthorConstantinidou, Anastasiaen


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