Browsing Breast Cancer Research by author "Kinnersley, Benjamin"
Now showing items 1-6 of 6
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Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.
Vijayakrishnan, J; Studd, J; Broderick, P; Kinnersley, B; Holroyd, A; et al. (NATURE PORTFOLIO, 2018-04-09)Genome-wide association studies (GWAS) have advanced our understanding of susceptibility to B-cell precursor acute lymphoblastic leukemia (BCP-ALL); however, much of the heritable risk remains unidentified. Here, we perform ... -
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
Melin, BS; Barnholtz-Sloan, JS; Wrensch, MR; Johansen, C; Il'yasova, D; et al. (NATURE PORTFOLIO, 2017-05-01)Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, but individual studies have had limited power to identify risk loci. We performed a meta-analysis of existing GWAS and two ... -
Impact of atopy on risk of glioma: a Mendelian randomisation study.
Disney-Hogg, L; Cornish, AJ; Sud, A; Law, PJ; Kinnersley, B; et al. (BMC, 2018-03-15)BACKGROUND: An inverse relationship between allergies with glioma risk has been reported in several but not all epidemiological observational studies. We performed an analysis of genetic variants associated with atopy to ... -
Influence of obesity-related risk factors in the aetiology of glioma.
Disney-Hogg, L; Sud, A; Law, PJ; Cornish, AJ; Kinnersley, B; et al. (SPRINGERNATURE, 2018-04-01)BACKGROUND: Obesity and related factors have been implicated as possible aetiological factors for the development of glioma in epidemiological observation studies. We used genetic markers in a Mendelian randomisation ... -
Mendelian randomisation study of the relationship between vitamin D and risk of glioma.
Takahashi, H; Cornish, AJ; Sud, A; Law, PJ; Kinnersley, B; et al. (NATURE PUBLISHING GROUP, 2018-02-05)To examine for a causal relationship between vitamin D and glioma risk we performed an analysis of genetic variants associated with serum 25-hydroxyvitamin D (25(OH)D) levels using Mendelian randomisation (MR), an approach ... -
Transcriptome-Wide Association Study Identifies New Candidate Susceptibility Genes for Glioma.
Atkins, I; Kinnersley, B; Ostrom, QT; Labreche, K; Il'yasova, D; et al. (AMER ASSOC CANCER RESEARCH, 2019-04-15)Genome-wide association studies (GWAS) have so far identified 25 loci associated with glioma risk, with most showing specificity for either glioblastoma (GBM) or non-GBM tumors. The majority of these GWAS susceptibility ...