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dc.contributor.authorRake, Cen_US
dc.contributor.authorGilham, Cen_US
dc.contributor.authorHatch, Jen_US
dc.contributor.authorDarnton, Aen_US
dc.contributor.authorHodgson, Jen_US
dc.contributor.authorPeto, Jen_US
dc.date.accessioned2018-08-29T11:12:26Z
dc.date.issued2009-03-31en_US
dc.identifier7en_US
dc.identifier.citationBRITISH JOURNAL OF CANCER, 2009, 100 pp. 1175 - 1183en_US
dc.identifier.issn0007-0920en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2406
dc.identifier.eissn1532-1827en_US
dc.identifier.doi10.1038/sj.bjc.6604879en_US
dc.description.abstractWe obtained lifetime occupational and residential histories by telephone interview with 622 mesothelioma patients (512 men, 110 women) and 1420 population controls. Odds ratios (ORs) were converted to lifetime risk (LR) estimates for Britons born in the 1940s. Male ORs (95% confidence interval (Cl)) relative to low-risk occupations for > 10 years of exposure before the age of 30 years were 50.0 (25.8-96.8) for carpenters (LR 1 in 17), 17.1 (10.3-28.3) for plumbers, electricians and painters, 7.0 (3.2-15.2) for other construction workers, 15.3 (9.0-26.2) for other recognised high-risk occupations and 5.2 (3.1-8.5) in other industries where asbestos may be encountered. The LR was similar in apparently unexposed men and women (similar to 1 in 1000), and this was approximately doubled in exposed workers’ relatives (OR 2.0, 95% Cl 1.3-3.2). No other environmental hazards were identified. In all, 14% of male and 62% of female cases were not attributable to occupational or domestic asbestos exposure. Approximately half of the male cases were construction workers, and only four had worked for more than 5 years in asbestos product manufacture. British Journal of Cancer (2009) 100, 1175-1183. doi: 10.1038/sj.bjc.6604879 www.bjcancer.comen_US
dc.format.extent1175 - 1183en_US
dc.languageEnglishen_US
dc.language.isoEnglishen_US
dc.publisherNATURE PUBLISHING GROUPen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.titleOccupational, domestic and environmental mesothelioma risks in the British population: a case-control studyen_US
dc.typeJournal Article
rioxxterms.versionofrecord10.1038/sj.bjc.6604879en_US
rioxxterms.licenseref.startdate2009-03-31en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfBRITISH JOURNAL OF CANCERen_US
pubs.notesaffiliation: Peto, J (Reprint Author), Inst Canc Res, Sutton SM2 5NG, Surrey, England. Rake, C.; Gilham, C.; Hatch, J.; Peto, J., Inst Canc Res, Sutton SM2 5NG, Surrey, England. Darnton, A.; Hodgson, J., Hlth & Safety Execut, Epidemiol Unit, Bootle L20 3QZ, Merseyside, England. Peto, J., Univ London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, England. keywords: mesothelioma; case-control; amosite keywords-plus: MALIGNANT MESOTHELIOMA; ASBESTOS EXPOSURE; PLEURAL MESOTHELIOMA; GREAT-BRITAIN; LUNG-CANCER; MORTALITY; SURVEILLANCE; DEATHS research-areas: Oncology web-of-science-categories: Oncology author-email: Julian.Peto@lshtm.ac.uk funding-acknowledgement: Carl Gibbons; Health & Safety Executive and Cancer Research UK funding-text: We thank Maria Kelly for the majority of the telephone interviews and also Jayne Simpson, Laura Newmark, Bavithra Vijayakumar, Chris Heaton, Samantha Warnakulasuriya, Qichen Liu, Katie Field and Emma Afify for administrative work on the study. Additional programming support was provided by Carl Gibbons, and independent advice was obtained from Ben Armstrong. Most importantly, we thank the cases and controls who agreed to participate. This research was supported by the Health & Safety Executive and Cancer Research UK. number-of-cited-references: 28 times-cited: 140 usage-count-last-180-days: 1 usage-count-since-2013: 16 journal-iso: Br. J. Cancer doc-delivery-number: 426ZO unique-id: ISI:000264747700021 oa: gold_or_bronze da: 2018-08-29en_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.volume100en_US
pubs.embargo.termsNot knownen_US
dc.contributor.icrauthorPeto, Julianen_US


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