Browsing Cancer Biology by author "Lee, Alexander"
Now showing items 1-4 of 4
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Drug repositioning in sarcomas and other rare tumors.
Lee, ATJ; Huang, PH; Pollack, SM; Jones, RL (ELSEVIER SCIENCE BV, 2016-03-17) -
Immune and muli-omic profiling for molecular classification and biomarker discovery in soft tissue sarcoma
Jones, R; Lee, A (Institute of Cancer Research (University Of London), 2020-02-29)Soft tissue sarcomas (STS) are a group of over 50 rare cancers of mesenchymal origin. Classification of STS is primarily based on histological characteristics of tumours. Novel biomarkers are required that account for the ... -
Phase III Soft Tissue Sarcoma Trials: Success or Failure?
Lee, ATJ; Pollack, SM; Huang, P; Jones, RL (SPRINGER, 2017-03-01)Two recently reported phase III randomised control trials (RCTs) have resulted in the registration of two new systemic therapies for advanced soft tissue sarcoma. Both of these trials' designs were informed by phase II ... -
The adequacy of tissue microarrays in the assessment of inter- and intra-tumoural heterogeneity of infiltrating lymphocyte burden in leiomyosarcoma.
Lee, ATJ; Chew, W; Wilding, CP; Guljar, N; Smith, MJ; et al. (NATURE PORTFOLIO, 2019-10-10)The characterisation and clinical relevance of tumour-infiltrating lymphocytes (TILs) in leiomyosarcoma (LMS), a subtype of soft tissue sarcoma that exhibits histological heterogeneity, is not established. The use of tissue ...